CAJ | 학술논문

目的：分析肝血色素沉着症磁共振（ MR） T2加权图像（ T2 WI）及梯度双回波T1加权图像（ T1 WI）的影像表现，评价MRI在肝血色素沉着症中的应用价值。方法回顾性分析确诊27例肝血色素沉着症患者MR图像，观察其T2 WI及梯度双回波T1 WI的肝脏信号改变。结果所有病例T2 WI均表现为肝脏实质信号不同程度减低，接近或低于同层面竖脊肌，肝脏在梯度双回波T1 WI同反相位均见信号减低，同相位图像上信号减低更明显，因此反相位信号高于同相位为其特异性征象，其中9例合并脾脏信号减低，脾脏信号反相位高于同相位。结论 T2 WI结合梯度双回波T1 WI对诊断肝血色素沉着症具有较高敏感性和特异性，MRI检查对肝血色素沉着症早期诊断和监测治疗具有重要临床价值。
목적：분석간혈색소침착증자공진（ MR） T2가권도상（ T2 WI）급제도쌍회파T1가권도상（ T1 WI）적영상표현，평개MRI재간혈색소침착증중적응용개치。방법회고성분석학진27례간혈색소침착증환자MR도상，관찰기T2 WI급제도쌍회파T1 WI적간장신호개변。결과소유병례T2 WI균표현위간장실질신호불동정도감저，접근혹저우동층면수척기，간장재제도쌍회파T1 WI동반상위균견신호감저，동상위도상상신호감저경명현，인차반상위신호고우동상위위기특이성정상，기중9례합병비장신호감저，비장신호반상위고우동상위。결론 T2 WI결합제도쌍회파T1 WI대진단간혈색소침착증구유교고민감성화특이성，MRI검사대간혈색소침착증조기진단화감측치료구유중요림상개치。
Objective To analyze the manifestations of MR T2 WI and dual echo T1 WI in liver hemochroma-tosis, and evaluate the value of MRI in the diagnosis of live hemochromatosis.Methods The MRI of 27 confirmed patients with liver hemochromatosis were retrospectively analyzed, the liver signal intensity on T2 WI and dual echo T1 WI were observed.Results All 27 patients′T2 WI showed liver signal intensity reduced in a certain extent, closed to or lower than the sacrospinal muscle signal intensity on the same slice.Dual-echo T1 WI also showed the liver sig-nal intensity reduced in both in-phase and opposed-phase images, however on the in-phase images the signal intensi-ty′s loss was more obvious than the opposed-phase images.The liver signal intensity was higher on the opposed-phase images than the in-phase images.Nine patients showed signal intensity reduced in spleen, and also display higher sig-nal intensity on opposed-phase images.Conclusion T2 WI combined with dual echo T1 WI have high degree of sensi-tivity and specificity for the diagnosis of hemochromatosis.MRI has very important clinical value for early diagnosis and treatment monitoring of hemochromatosis.