CAJ | 학술논문

目的：探讨万古霉素经静脉注射联合腰穿引流及鞘内注射古霉素治疗术后颅内感染的效果。方法采用Harrison标准诊断明确的术后颅内感染患者16例,均经静脉及鞘内应用万古霉素联合腰穿引流治疗。结果应用万古霉素0．5g,每日3次静点,万古霉素10mg加生理盐水稀释后鞘内注射,每日1~2次,平均治疗10d,本组16例全部治愈。结论鞘内注射联合静脉注射万古霉素及腰穿引流,提高了其在脑脊液中的浓度,加快的脑脊液的置换,可加快感染的控制,是治疗术后颅内感染有效方法。
목적：탐토만고매소경정맥주사연합요천인류급초내주사고매소치료술후로내감염적효과。방법채용Harrison표준진단명학적술후로내감염환자16례,균경정맥급초내응용만고매소연합요천인류치료。결과응용만고매소0．5g,매일3차정점,만고매소10mg가생리염수희석후초내주사,매일1~2차,평균치료10d,본조16례전부치유。결론초내주사연합정맥주사만고매소급요천인류,제고료기재뇌척액중적농도,가쾌적뇌척액적치환,가가쾌감염적공제,시치료술후로내감염유효방법。
Objective To investigate the efficacy of lumbar drainage of CSF( cerebrospinal fluid) and intravenous injec-tion of vancocin in treating postoperative intracranial infection. Methods 16 cases of postoperative intracranial infection were en-rolled in the study,according to Harrison criterion. Their clinical data was analyzed. Results 0. 5g vancocin was injected via intra-venous every 8 hours,and 10mg vancocin was administrated via intrathecal with 1~2 times per day. The 16 cases were cured with an average treatment duration of 10 days. Conclusion Drainage of CSF with the administration of vancocin via intravenous and in-trathecal approach is helpful to increase the vancocin density in CSF and to the refresh of the CSF. So it can faster the treatment of intracranial infection. It provide a useful and reliable method in treating postoperative intracranial infection.