河北医科大学学报
河北醫科大學學報
하북의과대학학보
JOURNAL OF HEBEI MEDICAL UNIVERSITY
2014年
10期
1144-1147
,共4页
肺炎%肌钙蛋白 I%肌酸激酶%儿童
肺炎%肌鈣蛋白 I%肌痠激酶%兒童
폐염%기개단백 I%기산격매%인동
pneumonia%troponin I%creatine kinase%children
目的：探讨小儿重症肺炎并发心肌损害中心肌钙蛋白I（cardiac troponin I，cTnI）的测定及其意义。方法选取重症肺炎患儿200例为观察组，轻症肺炎患儿180例为轻症组，正常儿童200例为对照组，对比3组儿童cTnI水平、肌酸激酶同工酶（creatine kinase MB，CK-MB）水平。结果观察组 cTnI、CK-MB、肌酸激酶（creatine kinase，CK）、乳酸脱氢酶（lactate dehydrogenase，LDH）及天冬氨酸转氨酶（aspartate amino-transferase，AST）水平高于轻症组（P＜0．05），观察组和轻症组 cTnI、CK-MB、LDH、AST水平高于对照组（P＜0．05）。观察组 cTnI阳性率高于轻症组（P＜0．05）。观察组与轻症组CK-MB阳性率差异无统计学意义（P＞0．05）。结论重症肺炎患儿多伴有不同程度的心肌损害，cTnI可作为监测心肌损伤的重要标志物。早期检测 cTnI有利于重症肺炎并发心急损害患儿的早期诊疗，从而预防心肌衰竭发生。
目的：探討小兒重癥肺炎併髮心肌損害中心肌鈣蛋白I（cardiac troponin I，cTnI）的測定及其意義。方法選取重癥肺炎患兒200例為觀察組，輕癥肺炎患兒180例為輕癥組，正常兒童200例為對照組，對比3組兒童cTnI水平、肌痠激酶同工酶（creatine kinase MB，CK-MB）水平。結果觀察組 cTnI、CK-MB、肌痠激酶（creatine kinase，CK）、乳痠脫氫酶（lactate dehydrogenase，LDH）及天鼕氨痠轉氨酶（aspartate amino-transferase，AST）水平高于輕癥組（P＜0．05），觀察組和輕癥組 cTnI、CK-MB、LDH、AST水平高于對照組（P＜0．05）。觀察組 cTnI暘性率高于輕癥組（P＜0．05）。觀察組與輕癥組CK-MB暘性率差異無統計學意義（P＞0．05）。結論重癥肺炎患兒多伴有不同程度的心肌損害，cTnI可作為鑑測心肌損傷的重要標誌物。早期檢測 cTnI有利于重癥肺炎併髮心急損害患兒的早期診療，從而預防心肌衰竭髮生。
목적：탐토소인중증폐염병발심기손해중심기개단백I（cardiac troponin I，cTnI）적측정급기의의。방법선취중증폐염환인200례위관찰조，경증폐염환인180례위경증조，정상인동200례위대조조，대비3조인동cTnI수평、기산격매동공매（creatine kinase MB，CK-MB）수평。결과관찰조 cTnI、CK-MB、기산격매（creatine kinase，CK）、유산탈경매（lactate dehydrogenase，LDH）급천동안산전안매（aspartate amino-transferase，AST）수평고우경증조（P＜0．05），관찰조화경증조 cTnI、CK-MB、LDH、AST수평고우대조조（P＜0．05）。관찰조 cTnI양성솔고우경증조（P＜0．05）。관찰조여경증조CK-MB양성솔차이무통계학의의（P＞0．05）。결론중증폐염환인다반유불동정도적심기손해，cTnI가작위감측심기손상적중요표지물。조기검측 cTnI유리우중증폐염병발심급손해환인적조기진료，종이예방심기쇠갈발생。
Objective To investigate the value of cardiac troponin I (CTnI)in children of severe pneumonia with myocardial damage.Methods A total of 200 children with severe pneumonia in our hospital were collected as observation group,180 children with mild pneumonia in our hospital in the same period were collected as mild group,200 cases of healthy children in the same period were collected as control group,CTnI level,creatine kinase MB(CK-MB)level of three groups were analyzed and compared.Results The cTnI,CK-MB,creatine Kinase (CK), lactate dehydrogenase(LDH)and aspartate amino-transferase,AST(AST)levels of observation group were significantly higher than those of mild group (P<0.05),and cTnI positive rate of observation group was significantly higher than that of mild group (P<0.05).The difference of CK-MB level between the two groups was not significant(P>0.05).Conclusion Most children of severe pneumonia are associated with varying degrees of myocardial damage,cTnI can be used to monitor the condition of the children as an important marker of myocardial inj ury.Early detection of cTnI is favorable to the early diagnosis and treatment of severe pneumonia with myocardial damage,thereby preventing the occurrence of cardiac failure in the children.
