CAJ | 학술논문

目的：比较尿毒净液与肾康注射液治疗慢性肾衰竭(CRF)的临床疗效。方法：选取52例CRF患者随机分为对照组和观察组各26例，对照组在西医治疗基础上加用肾康注射液治疗，观察组在西医治疗基础上加用尿毒净液治疗，观察比较2组疗效。结果：观察组和对照组的总有效率分别为84.62%和80.77%(χ2=10.50， P＞0.05)。治疗后2组内生肌酐清除率(CCr)、血尿素氮(BUN)和血肌酐(SCr)水平相似(P＞0.05)，均较治疗前显著改善(P＜0.05)。结论：尿毒净液治疗CRF的临床疗效与肾康注射液相当。
목적：비교뇨독정액여신강주사액치료만성신쇠갈(CRF)적림상료효。방법：선취52례CRF환자수궤분위대조조화관찰조각26례，대조조재서의치료기출상가용신강주사액치료，관찰조재서의치료기출상가용뇨독정액치료，관찰비교2조료효。결과：관찰조화대조조적총유효솔분별위84.62%화80.77%(χ2=10.50， P＞0.05)。치료후2조내생기항청제솔(CCr)、혈뇨소담(BUN)화혈기항(SCr)수평상사(P＞0.05)，균교치료전현저개선(P＜0.05)。결론：뇨독정액치료CRF적림상료효여신강주사액상당。
Objective:To compare clinical effects of urea nitrogen cleaning fluid and ShenKang injection in treating chronic renal failure (CRF). Methods:Fifty-two CRF patients were randomized into the control group and the observation group, the control group were given with ShenKang injection on the foundation of western medicine and the observatioin group urea nitrogen cleaning fluid, curative effects of both groups were observed and compared. Results:Total effective rates of the observation group and the control group were 84.62%and 80.77%respectively (χ2=10.50, P>0.05). Endogenous creatinine clearance (CCr), the levels of blood urea nitrogen (BUN) and serum creatinine (SCr) of both groups were similar after treating (P>0.05), they were improved significantly compared with before treating (P<0.05). Conclusion:Urea nitrogen cleaning fluid shows similar effects to ShenKang Injection in the treatment for CRF.