西部中医药
西部中醫藥
서부중의약
GANSU JOURNAL OF TRADITIONAL CHINESE MEDICINE
2014年
10期
77-79
,共3页
关节置换%预防用药%围手术期%抗菌药物%头孢菌素类%用药时间%外科手术
關節置換%預防用藥%圍手術期%抗菌藥物%頭孢菌素類%用藥時間%外科手術
관절치환%예방용약%위수술기%항균약물%두포균소류%용약시간%외과수술
joint replacement%preventive medication%perioperative period%antibacterial drugs%cephalosporins%medication time%surgery
目的：了解甘肃省中医院关节置换手术患者围手术期抗菌药物的使用情况。方法：对2010年1月至2012年12月出院的647例关节置换手术患者围手术期抗菌药物的种类、给药天数、联用情况、用药时间等情况进行统计分析。结果：调查的手术中以全髋关节置换术为主，占52.40%；有94.40%的患者在术前0.5～2小时进行预防性给药，术后抗菌药物使用时间超过48小时者占96.10%。术前预防使用的抗菌药物中，主要以一代头孢菌素类(33.40%)和β-内酰胺酶抑制剂(31.50%)为主，预防用药以单用为主，占79.80%，其次为二联用药，占18.70%。术后抗菌药物使用3～7天的最多，占88.56%。结论：关节置换手术抗菌药物预防用药存在术后用药时间偏长、联合用药的现象，还存在手术时间超过3小时及手术失血超过1500 mL的患者术中未使用抗生素等问题，有必要加强我院外科手术预防性使用抗菌药物的管理，进一步规范抗菌药物的合理应用。
目的：瞭解甘肅省中醫院關節置換手術患者圍手術期抗菌藥物的使用情況。方法：對2010年1月至2012年12月齣院的647例關節置換手術患者圍手術期抗菌藥物的種類、給藥天數、聯用情況、用藥時間等情況進行統計分析。結果：調查的手術中以全髖關節置換術為主，佔52.40%；有94.40%的患者在術前0.5～2小時進行預防性給藥，術後抗菌藥物使用時間超過48小時者佔96.10%。術前預防使用的抗菌藥物中，主要以一代頭孢菌素類(33.40%)和β-內酰胺酶抑製劑(31.50%)為主，預防用藥以單用為主，佔79.80%，其次為二聯用藥，佔18.70%。術後抗菌藥物使用3～7天的最多，佔88.56%。結論：關節置換手術抗菌藥物預防用藥存在術後用藥時間偏長、聯閤用藥的現象，還存在手術時間超過3小時及手術失血超過1500 mL的患者術中未使用抗生素等問題，有必要加彊我院外科手術預防性使用抗菌藥物的管理，進一步規範抗菌藥物的閤理應用。
목적：료해감숙성중의원관절치환수술환자위수술기항균약물적사용정황。방법：대2010년1월지2012년12월출원적647례관절치환수술환자위수술기항균약물적충류、급약천수、련용정황、용약시간등정황진행통계분석。결과：조사적수술중이전관관절치환술위주，점52.40%；유94.40%적환자재술전0.5～2소시진행예방성급약，술후항균약물사용시간초과48소시자점96.10%。술전예방사용적항균약물중，주요이일대두포균소류(33.40%)화β-내선알매억제제(31.50%)위주，예방용약이단용위주，점79.80%，기차위이련용약，점18.70%。술후항균약물사용3～7천적최다，점88.56%。결론：관절치환수술항균약물예방용약존재술후용약시간편장、연합용약적현상，환존재수술시간초과3소시급수술실혈초과1500 mL적환자술중미사용항생소등문제，유필요가강아원외과수술예방성사용항균약물적관리，진일보규범항균약물적합리응용。
Objective:To investigate the conditions of antibacterial drugs applied to the patients in periopera-tive period after joint replacement surgery in Gansu Provincial Hospital of Traditional Chinese Medicine. Methods:The kinds of antibacterial drugs, medication days, the combination, medication time and other conditions of 647 pa-tients undergoing joint replacement surgery, who were discharged from January, 2010 to December, 2012, were ana-lyzed statistically. Results:The patient were performed with total hip replacement (THR) mainly, and they occupied 52.40%; 94.40% of the patients took preventive medicine at the time of half of the hour to two hours before the surgery, the patients taking antibacterial drugs more than 48 hours after the surgery reached 96.10%. Antibacterial drugs taken before the surgery for the prevention were cephalosporins generation one (33.40%) andβ-lactamase in-hibitor (31.50%) mainly, preventive medication was using single drug usually, and it occupied 79.80%, the next was the combination of two drugs and it reached 18.70%. The medication time of antibacterial drugs after the surgery was from three to seven days mostly and it occupied 88.56%. Conclusion: Preventive medication of antibacterial drugs for the patients with joint replacement surgery presents the problems of medication time too long after the surgery, the combination of drugs, the patients with surgical time more than three hours and bleeding volume over 1 500 mL didn't use antibacterial drugs, it is necessary to enhance antibacterial drugs management in preventive medi-cation of surgery in our hospital, therefore to regulate rational use of antibacterial drugs.
