CAJ | 학술논문

目的：通过检测脓毒症患者血清脂联素水平，探讨其与脓毒症患者预后的关系。方法：选取脓毒症患者110例为观察组（脓毒症组），健康体检者100例为对照组，检测其血清脂联素水平并进行比较，分析脓毒症患者临床资料及预后，采用多因素 Logistic 回归分析。结果：脓毒症患者血清脂联素水平低于对照组，差异有统计学意义（P ＜0．05）；脓毒症死亡组血清脂联素水平低于脓毒症生存组，差异有统计学意义（P ＜0．05）；年龄、MODS、脂联素与脓毒症死亡存在密切相关性（P ＜0．05），为脓毒症患者死亡的独立危险因素。结论：脓毒症患者脂联素水平越低，死亡率越高，脂联素可作为预测患者预后的指标。
목적：통과검측농독증환자혈청지련소수평，탐토기여농독증환자예후적관계。방법：선취농독증환자110례위관찰조（농독증조），건강체검자100례위대조조，검측기혈청지련소수평병진행비교，분석농독증환자림상자료급예후，채용다인소 Logistic 회귀분석。결과：농독증환자혈청지련소수평저우대조조，차이유통계학의의（P ＜0．05）；농독증사망조혈청지련소수평저우농독증생존조，차이유통계학의의（P ＜0．05）；년령、MODS、지련소여농독증사망존재밀절상관성（P ＜0．05），위농독증환자사망적독립위험인소。결론：농독증환자지련소수평월저，사망솔월고，지련소가작위예측환자예후적지표。
Objective To investigate the relationship between the serum adiponectin levels and prognosis of septic patients, by detecting the serum levels of adiponectin in septic patients. Methods 110 septic patients and 100 healthy controls subjects were enrolled. The serum levels of adiponectin were measured and compared. Clinical data and outcomes of septic patients were analyzed multi-factor Logistic regression analysis were used. Results The serum levels of adiponectin in septic patients were lower than that in healthy controls (P < 0.05). Serum levels of adiponectin in death group was lower than that in sepsis survival group (P < 0.05). There were close correlations between age, MODS, adiponectin and sepsis death(P < 0.05), which were the independent risk factors of death in septic patients. Conclusion The lower the adiponectin level is, the higher mortality rate occurs.Adiponectin can be used as the indicators of patients′ prognosis.