CAJ | 학술논문

目的：探讨国医大师颜正华教授处方用药规律。方法在收集颜正华教授含茯苓处方的基础上，利用中医传承辅助系统构建数据库，使用软件的统计报表模块、数据分析模块，采用关联规则、apriori算法等数据挖掘方法，分析含茯苓处方中单味药物频次、药物组合频次、关联规则与核心药物组合等。结果含茯苓处方常用于治疗眩晕、胃痛、泄泻等病证，高频药物包括陈皮、赤芍、丹参、炒酸枣仁、首乌藤等，高频药物组合包括“陈皮，茯苓”、“丹参，茯苓”、“茯苓，炒酸枣仁”等，置信度≥0.9的关联规则包括“龙骨→牡蛎”、“茯苓，龙骨→牡蛎”、“牡蛎，首乌藤→龙骨”、“炒白术→茯苓”等。结论颜正华教授含茯苓处方所用药物多具理气、安神、凉血等功效，用药较为集中，组方法度清晰。
목적：탐토국의대사안정화교수처방용약규률。방법재수집안정화교수함복령처방적기출상，이용중의전승보조계통구건수거고，사용연건적통계보표모괴、수거분석모괴，채용관련규칙、apriori산법등수거알굴방법，분석함복령처방중단미약물빈차、약물조합빈차、관련규칙여핵심약물조합등。결과함복령처방상용우치료현훈、위통、설사등병증，고빈약물포괄진피、적작、단삼、초산조인、수오등등，고빈약물조합포괄“진피，복령”、“단삼，복령”、“복령，초산조인”등，치신도≥0.9적관련규칙포괄“용골→모려”、“복령，용골→모려”、“모려，수오등→용골”、“초백술→복령”등。결론안정화교수함복령처방소용약물다구리기、안신、량혈등공효，용약교위집중，조방법도청석。
Objective To explore the medication rules of state medical master Yan Zhenghua from the prescriptions. Methods After analyzed by the statistical report module and the data analysis module, the method of data-mining that including association rules and apriori algorithm was used to analyze the frequency of Poria and drug combination, the association rules between drugs and core drug combinations in Pro. Yan’s prescriptions via a database based on Traditional Chinese Medicine (TCM) inheritance assist system. Results The prescriptions containing Poria were commonly used to treat vertigo, stomachache, diarrhea and other syndromes. The highest frequently used drugs were Pericarpium Citri Reticulatae, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Parched Semen Ziziphi Spinosae, and Caulis Polygoni Multiflori. The most frequently used drug combinations were “Pericarpium Citri Reticulatae, Poria”, “Radix Salviae Miltiorrhizae, Poria”, and“Poria, Parched Semen Ziziphi Spinosae”. The drug association rules that the confidence coefficient was more than 0.9 were “Carina→Oyster”, “Poria, Carina→Oyster”,“Oyster, Caulis Polygoni Multiflori→Carina”, and“Rhizoma Atractylodis Macrocephalae→Poria”. Conclusion The drugs in the prescriptions containing Poria that built by Pro. Yan mostly had the effects of regulating the flow of qi, relieving uneasiness of body and mind, and cooling the blood, which reflected the clearly thought when Pro. Yan made the prescriptions.