浙江临床医学
浙江臨床醫學
절강림상의학
ZHEJIANG CLINICAL MEDICAL JOURNAL
2014年
10期
1560-1561,1562
,共3页
输尿管下段结石%体外冲击波碎石术%盐酸坦洛新缓释胶囊
輸尿管下段結石%體外遲擊波碎石術%鹽痠坦洛新緩釋膠囊
수뇨관하단결석%체외충격파쇄석술%염산탄락신완석효낭
Lower Ureteral Calculi%Extracorporeal Shock Wave%Lithotripsy
目的：探讨对输尿管下段结石患者行体外冲击波碎石术（ESWL）后应用盐酸坦洛新缓释胶囊辅助排石的临床效果。方法将80例输尿管下段结石患者ESWL术后按照随机数方法分为观察组和对照组，各40例，对照组行抗感染及运动等常规治疗，观察组在此基础上口服盐酸坦洛新缓释胶囊。以术后首日检查结果为参考值，通过B超或腹部X线平片动态观察术后3d、7d、2周和4周的结石排净率、术后4周的临床治疗疗效、结石排净时间、肾绞痛发生率及VAS评分等。结果观察组患者术后3d、7d时的结石排净率分别为42.5%与52.5%，与对照组间差异无统计学意义；观察组第2周、4周的结石排净率为85.0%、95.0%，高于同期对照组的50.0%与67.5%，差异有统计学意义（P<0.05）。观察组治愈26例，有效12例，有效率95.0%，对照组治愈15例，有效13例，有效率70.0%，观察组临床有效率显著高于对照组（P<0.05）。观察组的结石排净时间（6.52±1.74）d，显著短于对照组的（9.41±2.73）d，差异有统计学意义（P<0.05）；观察组VAS评分为（2.29±1.35）分，低于对照组的（3.81±1.24）分，差异有统计学意义（P<0.05）。结论输尿管下段结石患者体外冲击波碎石术后，给予口服盐酸坦洛新缓释胶囊，排石效果确切且安全可靠，同时肾绞痛发生率较低。
目的：探討對輸尿管下段結石患者行體外遲擊波碎石術（ESWL）後應用鹽痠坦洛新緩釋膠囊輔助排石的臨床效果。方法將80例輸尿管下段結石患者ESWL術後按照隨機數方法分為觀察組和對照組，各40例，對照組行抗感染及運動等常規治療，觀察組在此基礎上口服鹽痠坦洛新緩釋膠囊。以術後首日檢查結果為參攷值，通過B超或腹部X線平片動態觀察術後3d、7d、2週和4週的結石排淨率、術後4週的臨床治療療效、結石排淨時間、腎絞痛髮生率及VAS評分等。結果觀察組患者術後3d、7d時的結石排淨率分彆為42.5%與52.5%，與對照組間差異無統計學意義；觀察組第2週、4週的結石排淨率為85.0%、95.0%，高于同期對照組的50.0%與67.5%，差異有統計學意義（P<0.05）。觀察組治愈26例，有效12例，有效率95.0%，對照組治愈15例，有效13例，有效率70.0%，觀察組臨床有效率顯著高于對照組（P<0.05）。觀察組的結石排淨時間（6.52±1.74）d，顯著短于對照組的（9.41±2.73）d，差異有統計學意義（P<0.05）；觀察組VAS評分為（2.29±1.35）分，低于對照組的（3.81±1.24）分，差異有統計學意義（P<0.05）。結論輸尿管下段結石患者體外遲擊波碎石術後，給予口服鹽痠坦洛新緩釋膠囊，排石效果確切且安全可靠，同時腎絞痛髮生率較低。
목적：탐토대수뇨관하단결석환자행체외충격파쇄석술（ESWL）후응용염산탄락신완석효낭보조배석적림상효과。방법장80례수뇨관하단결석환자ESWL술후안조수궤수방법분위관찰조화대조조，각40례，대조조행항감염급운동등상규치료，관찰조재차기출상구복염산탄락신완석효낭。이술후수일검사결과위삼고치，통과B초혹복부X선평편동태관찰술후3d、7d、2주화4주적결석배정솔、술후4주적림상치료료효、결석배정시간、신교통발생솔급VAS평분등。결과관찰조환자술후3d、7d시적결석배정솔분별위42.5%여52.5%，여대조조간차이무통계학의의；관찰조제2주、4주적결석배정솔위85.0%、95.0%，고우동기대조조적50.0%여67.5%，차이유통계학의의（P<0.05）。관찰조치유26례，유효12례，유효솔95.0%，대조조치유15례，유효13례，유효솔70.0%，관찰조림상유효솔현저고우대조조（P<0.05）。관찰조적결석배정시간（6.52±1.74）d，현저단우대조조적（9.41±2.73）d，차이유통계학의의（P<0.05）；관찰조VAS평분위（2.29±1.35）분，저우대조조적（3.81±1.24）분，차이유통계학의의（P<0.05）。결론수뇨관하단결석환자체외충격파쇄석술후，급여구복염산탄락신완석효낭，배석효과학절차안전가고，동시신교통발생솔교저。
Objective To explore the clinical effect of tamsulosin hydrochloride sustained-release gel adjuvant row stone after lower ureteral calculi extracorporeal shock wave lithotripsy. Method 80 cases of ureteral calculi patients in our hospital underwent ESWL operation from 2012 January to 2014 April were divided into the observation group and the control group with 40 cases in each randomly.80 patients were treated with ESWL,control group treated with anti - infection and sports conventional treatment,the observation group received oral Tamsulosin Hydrochloride Sustained-release Capsules based on the control group.Taking on the first postoperative day findings as the reference value,the stone clearance rate after 3 days,7 days,2 weeks and 4 weeks were observed by B ultrasound or abdominal X-ray dynamic,and the clinical curative effect of the treatment after 4 weeks,the lithagogue time, incidence of renal colic and VAS score were recorded. Result The patients in observation group 3 days,7 days calculi discharge rate were 42.5%and 52.5%,P>0.05.Observation group of 2 weeks and 4 weeks,calculi discharge rate were 85%,95%,higher than that of control group at the same time(50%and 67.5%),P<0.05.In the observation group,26 cases were cured,12 cases effective, efficiency was 95%.In the control group,15 cases were cured,13 cases effective,the efficiency was 70%,P<0.05.The observed group lithagogue time was (6.52±1.74)d,significantly lower than the control group (9.41±2.73) d,P<0.05.The observation group VAS was (2.29±1.35),lower than that of the control group (3.81±1.24),the difference was statistically significant, P<0.05. Conclusion After extracorporeal shock wave lithotripsy of ureteral stones in the lower segment of patients,treated with oral Tamsulosin Hydrochloride Sustained-release. Capsules could row of stone effect with safety,and the incidence of renal colic is low and can be widely applied in clinical practice.
