CAJ | 학술논문

目的：评价通心络胶囊对糖尿病性周围神经病变患者神经传导速度作用的有效性。方法：计算机检索Cochrane图书馆临床对照试验资料库、Pubmed Embase、中国生物医学文献数据库、中国期刊全文数据库、万方期刊数据库等相关资料，按照Co－chrane系统评价的方法，客观评价纳入研究的质量，提取有效数据，采用RevMan 5．2软件进行Meta分析。结果：共纳入14个随机对照试验，包括1078例患者。结果显示，与对照组相比，通心络胶囊能进一步提高正中神经及腓总神经的运动神经传导速度[SMD＝－1．10，95％CI（－1．54，－0．65），P＜0．01]，[SMD＝－1．83，95％CI（－2．35，－1．30），P＜0．01]；提高正中神经及腓总神经的感觉神经传导速度[SMD＝－1．27，95％CI（－1．80，－0．75），P＜0．01]，[SMD＝－1．60，95％CI（－2．39，－0．81）， P＜0．01]。结论：通心络胶囊对糖尿病性周围神经病变患者神经传导速度作用是有效的。
목적：평개통심락효낭대당뇨병성주위신경병변환자신경전도속도작용적유효성。방법：계산궤검색Cochrane도서관림상대조시험자료고、Pubmed Embase、중국생물의학문헌수거고、중국기간전문수거고、만방기간수거고등상관자료，안조Co－chrane계통평개적방법，객관평개납입연구적질량，제취유효수거，채용RevMan 5．2연건진행Meta분석。결과：공납입14개수궤대조시험，포괄1078례환자。결과현시，여대조조상비，통심락효낭능진일보제고정중신경급비총신경적운동신경전도속도[SMD＝－1．10，95％CI（－1．54，－0．65），P＜0．01]，[SMD＝－1．83，95％CI（－2．35，－1．30），P＜0．01]；제고정중신경급비총신경적감각신경전도속도[SMD＝－1．27，95％CI（－1．80，－0．75），P＜0．01]，[SMD＝－1．60，95％CI（－2．39，－0．81）， P＜0．01]。결론：통심락효낭대당뇨병성주위신경병변환자신경전도속도작용시유효적。
Objective:To evaluate efficacy of Tongxinluo capsule in improving the nerve conduction velocity of patients with diabetic pe-ripheral neuropathy.Methods:Randomized controlled trials were electronically retrieved from Cochrane Library,Pubmed Embase,CBM, CNKI,Wanfang Database,and so on.All articles were assessed according to the Cochrane Handbook for Systematic Reviews of interven-tions and then effective data were analyzed by RevMan 5.2 soft ware.Results:Fourteen randomized controlled trials involving 1078 pa-tients were included.Results of Meta-analysis showed that there was statistical difference in the motor nerve conduction velocity of median nerve and common peroneal nerve[SMD=-1.10,95%CI(-1.54,-0.65),P<0.01]and[SMD=-1.83,95% CI( -2.35,-1. 30),P<0.01.the sensory nerve conduction velocity of Median nerve and common peroneal nerve were improved[SMD=-1.27,95%CI(-1.80,-0.75),P<0.01]and[SMD=-1.60,95%CI(-2.39,-0.81),P<0.01].Conclusion:The treatment plan of Tongx-inluo capsule for Diabetic Peripheral Neuropathy is efficacy.