CAJ | 학술논문

目的：观察硫酸氢氯吡格雷片联合阿托伐他汀钙胶囊、养心氏片治疗冠心病PCI术后心绞痛的疗效。方法：将78例患者随机分为治疗组和对照组，治疗组39例，用硫酸氢氯吡格雷片联合阿托伐他汀钙胶囊、养心氏片治疗；对照组用辛伐他汀片联合阿司匹林肠溶片治疗，2组治疗12周后判断疗效。治疗前后测定TC、TG、HDL－C和LDL－C水平。结果：治疗组显效率为93．31％，对照组显效率为74．36％（2组比较P＜0．01）；2组TG、TC、LDL－C均较治疗前明显降低（P＜0．01），而HDL－C较治疗前明显升高（ P＜0．01）。结论：硫酸氢氯吡格雷片联合阿托伐他汀钙胶囊、养心氏片是治疗冠心病PCI术后心绞痛的有效药物组合，能有效降低心血管事件的发生率。
목적：관찰류산경록필격뢰편연합아탁벌타정개효낭、양심씨편치료관심병PCI술후심교통적료효。방법：장78례환자수궤분위치료조화대조조，치료조39례，용류산경록필격뢰편연합아탁벌타정개효낭、양심씨편치료；대조조용신벌타정편연합아사필림장용편치료，2조치료12주후판단료효。치료전후측정TC、TG、HDL－C화LDL－C수평。결과：치료조현효솔위93．31％，대조조현효솔위74．36％（2조비교P＜0．01）；2조TG、TC、LDL－C균교치료전명현강저（P＜0．01），이HDL－C교치료전명현승고（ P＜0．01）。결론：류산경록필격뢰편연합아탁벌타정개효낭、양심씨편시치료관심병PCI술후심교통적유효약물조합，능유효강저심혈관사건적발생솔。
Objective:To observe the clinical efficacy of the Clopidogrel Bisulfate tablets combined with Atorvastatin Calcium capsules and Yangxinshi tablets on angina pectoris patients after PCI.Methods:Seventy eight patients were randomly divided into the treatment group (n=39) and the control group (n=39).Patients in the treatment group were given Clopidogrel Bisulfate tablets combined with Atorvastatin Calcium capsules and Yangxinshi tablets, and the control group applied Simvastatin tablets combined with Aspirin Enteric-coated tablets.The therapeutic effects of the two groups were evaluated after 12 weeks of treatment.The relevant indicators levels were measured, such as TC, TG, HDL-C and LDL-C.Results: The effective rates of the treatment group and control group were 93.31%and 74.36%(P<0.01).The levels of TG and TC and LDL-C, were significantly lower after treatment in both two groups, while the level of HDL-C was significantly increased in treatment group.Conclusion: The combination therapy of Clopidogrel Bisulfate tablets, Atorvastatin Calcium capsules and Yangxinshi tablets is an available drug combination for the treatment of angina pectoris after PCI, and it can effectively reduce the incidence of cardiovascular events.