CAJ | 학술논문

文章简要介绍了队列研究的方法及其在中医药疗效评价中应用的可行性；比较详尽地介绍了作为疗效评价的队列研究其证据的等级、方法学的优点和局限性，并讨论了队列研究用于中医药临床疗效评价的方法学要点，如中医药暴露水平划分、结局指标的选择、起始暴露的确定以及最终暴露组的划归、队列迁移的控制、盲法以及安慰剂的使用、随访及统计分析过程中可能会遇到的问题。希望对中医药疗效评价研究采用队列研究设计提供参考。
문장간요개소료대렬연구적방법급기재중의약료효평개중응용적가행성；비교상진지개소료작위료효평개적대렬연구기증거적등급、방법학적우점화국한성，병토론료대렬연구용우중의약림상료효평개적방법학요점，여중의약폭로수평화분、결국지표적선택、기시폭로적학정이급최종폭로조적화귀、대렬천이적공제、맹법이급안위제적사용、수방급통계분석과정중가능회우도적문제。희망대중의약료효평개연구채용대렬연구설계제공삼고。
We introduced briefly the methodological key points of cohort study,and focused on the evidence level,methodological pros and cons as well as challenges of cohorts for clinical therapeutic effect evaluation.We discussed the special methodological issues related to clinical effectiveness evaluation of traditional Chinese medicine(TCM),including classification of TCM exposure levels,selection of outcomes,initial exposure and thorough exposure,control of migration of cohorts,use of blinding and placebo,follow-ups and some sta-tistics issues.