CAJ | 학술논문

[目的]探讨中华蟾蜍（ Bufo bufo gargarizans）胚后嗅球神经元自发电活的电生理学特性的发育变化。[方法]应用微电极电生理技术，对中华蟾蜍胚后嗅球神经元的自发放电活动进行在体胞外记录。[结果]随着嗅球的发育，其神经元的放电形式逐渐增多，单个放电振幅逐渐增大，且在变态期达最大；连续放电振幅在胚后发育的中期变化不大，但高于发育的早期和成体期；连续簇状放电频率随着发育时期而降低，但在成体期再次升高，而连续单个放电频率只在成体期增大。[结论]随着嗅球的发育，神经元的兴奋性逐步提高，神经元电活动形式逐渐呈现多样化。
[목적]탐토중화섬서（ Bufo bufo gargarizans）배후후구신경원자발전활적전생이학특성적발육변화。[방법]응용미전겁전생리기술，대중화섬서배후후구신경원적자발방전활동진행재체포외기록。[결과]수착후구적발육，기신경원적방전형식축점증다，단개방전진폭축점증대，차재변태기체최대；련속방전진폭재배후발육적중기변화불대，단고우발육적조기화성체기；련속족상방전빈솔수착발육시기이강저，단재성체기재차승고，이련속단개방전빈솔지재성체기증대。[결론]수착후구적발육，신경원적흥강성축보제고，신경원전활동형식축점정현다양화。
Objective] The aim of this study was to investigate the electrophysiological characteristics of spontaneous electrical activities of olfactory bulb in Bufo gargarizans during postembryonic development. [Method] Microelectrode technique was used to record extracellular spontaneous electrical activities of olfactory bulb in B. gar-garizans. [Result] Along with the development of olfactory bulb, the discharge types increased gradual y. Single spontaneous firing enhanced gradual y and it reached the maximum in the metamorphosis phase. The intensity of consecutive single sponta-neous firing changed slightly at the middle of post-embryonic development, but it was stil higher than in the early phase and the adult phase. Consecutive burst spontaneous firing frequency went down over time. [Conclusion] Along with the de-velopment of olfactory bulb, the neuronal excitability increases step by step and the neuronal electrical activities diversify gradual y.