CAJ | 학술논문

目的：探讨高同型半胱氨酸(HCY)血症患者中医体质类型分布与中医证素的关系。方法对本院1316例糖尿病、冠心病、高血压及脑梗死患者进行调查,纳入326例高HCY血症患者的四诊资料,进行体质判定,同时应用证素辨证方法行证素判断,分析体质与证素的相关性。结果调查人群中高HCY血症患病率为24.77%,其中平和质6例,偏颇体质320例。偏颇体质中痰湿质、瘀血质、气虚质分别为110、73、59例。血瘀、痰浊、气虚、湿为高HCY血症患者的主要证素,分别为100、98、73、37例。痰湿体质与证素痰一致性最强(Kappa＝0.89,P＜0.05)。结论痰湿质、瘀血质、气虚质是高 HCY 血症患者的常见体质,血瘀、痰浊、气虚、湿为高HCY血症患者的主要病性证素特点,两者结果存在一致性,证素痰浊与痰湿体质一致性最强。
목적：탐토고동형반광안산(HCY)혈증환자중의체질류형분포여중의증소적관계。방법대본원1316례당뇨병、관심병、고혈압급뇌경사환자진행조사,납입326례고HCY혈증환자적사진자료,진행체질판정,동시응용증소변증방법행증소판단,분석체질여증소적상관성。결과조사인군중고HCY혈증환병솔위24.77%,기중평화질6례,편파체질320례。편파체질중담습질、어혈질、기허질분별위110、73、59례。혈어、담탁、기허、습위고HCY혈증환자적주요증소,분별위100、98、73、37례。담습체질여증소담일치성최강(Kappa＝0.89,P＜0.05)。결론담습질、어혈질、기허질시고 HCY 혈증환자적상견체질,혈어、담탁、기허、습위고HCY혈증환자적주요병성증소특점,량자결과존재일치성,증소담탁여담습체질일치성최강。
Objective To investigate the relationship of TCM constitution and syndrome elements based on patients with hyperhomocysteinemia. Methods A survey was conducted among 1316 patients with diabetes, coronary disease, hypertension and cerebral infarction. Totally 326 patients with hyperhomocysteinemia were incorporated in diagnostic data and their constitutions were determined. At the same time, syndrome elements identification method for syndrome elements was applied for judgment, and consistency of the constitution and syndrome elements was analyzed. Results The survey showed that prevalence rate of population with hyperhomocysteinemia was 24.77%;there were 6 cases with mild nature, and 320 cases with biased constitution;phlegm dampness, blood stasis, qi deficiency of constitutions 110 cases, 73 cases and 59 cases, respectively;blood stasis, phlegm, qi deficiency, and dampness were the main syndrome elements of hyperhomocysteinemia, of 100 cases, 98 cases, 73 cases and 59 cases, respectively;the consistency of phlegm dampness constitution and syndromes of phlegm was the most obvious (Kappa=0.89, P<0.05). Conclusion Phlegm dampness, blood stasis, and qi deficiency were the most common constitutions of hyperhomocysteinemia;blood stasis, phlegm, qi deficiency and dampness were the main syndrome elements of hyperhomocysteinemia patients. The two results were consistent, and the consistency of phlegm syndrome and phlegm dampness constitution was the most obvious.