CAJ | 학술논문

针对当前DNA序列图形表达模式中存在简并现象的相关问题，提出了一种新的二元符号图形表达方式。将四类碱基的编码过程看成是构成DNA序列的元素在直角坐标平面上的移动过程，以两种不同的标志符号来解决可能出现的元素重叠情况。此方案所标志的图形不存在自交现象，从而在DNA序列和图形表达之间建立了一一对应的关系。通过实例说明该方法在对无向图和有向图表达中均能有效地降低图形简并度，并引入人工代谢系统中的编码模式作为分析工具对DNA序列进行比较分析；以代谢中间物值作为参数，研究不同物种的DNA序列之间的相似性。实例分析表明，该参数能较好地表征不同物种之间的相似性程度高低，是一种简便可行的DNA序列特征的比较方法。
침대당전DNA서렬도형표체모식중존재간병현상적상관문제，제출료일충신적이원부호도형표체방식。장사류감기적편마과정간성시구성DNA서렬적원소재직각좌표평면상적이동과정，이량충불동적표지부호래해결가능출현적원소중첩정황。차방안소표지적도형불존재자교현상，종이재DNA서렬화도형표체지간건립료일일대응적관계。통과실례설명해방법재대무향도화유향도표체중균능유효지강저도형간병도，병인입인공대사계통중적편마모식작위분석공구대DNA서렬진행비교분석；이대사중간물치작위삼수，연구불동물충적DNA서렬지간적상사성。실례분석표명，해삼수능교호지표정불동물충지간적상사성정도고저，시일충간편가행적DNA서렬특정적비교방법。
This paper proposed a novel representation mode based on binary-symbol for degeneracy in undirected graph and directed graph based on DNA sequences.This method transferd the coding process for four bases to the moving process of ele-ments which composed DNA sequences on the rectangular coordinates.It used two different symbols to express overlapping ele-ments in the kind of graphical representation.Graphical curve could not overlap under this mechanism.One DNA sequence had unique graphical representation and vice verse.Degeneracy in undirected graph and directed graph could be decreased in some examples by this method.As a tool,codes mode based on artificial metabolic system could be used for different DNA se-quences comparison.It researched similarity in DNA sequences in different animals based on metabolic intermediate.From the experiments it can conclude that the parameter can illustrate similarity degree among different animals and it is convenient method for discussing DNA sequences feature.