CAJ | 학술논문

肌醇是自然界中广泛存在的一种六元醇，有广泛的生理、生化作用，特别是能够促进肝和其他组织中的脂肪代谢、降低血中胆固醇，临床用于治疗脂肪肝、肝硬化，动脉硬化及高血脂症。近年来，一些肌醇衍生物已被报道具有其他生物活性，包括降血糖、镇咳，抗炎等作用，其中，松醇、白坚木皮醇、红杉醇等肌醇单甲醚类衍生物的研究较为深入，本文重点对这些肌醇单甲醚类衍生物的生物活性、提取制备和开发应用等方面进行综述。
기순시자연계중엄범존재적일충륙원순，유엄범적생리、생화작용，특별시능구촉진간화기타조직중적지방대사、강저혈중담고순，림상용우치료지방간、간경화，동맥경화급고혈지증。근년래，일사기순연생물이피보도구유기타생물활성，포괄강혈당、진해，항염등작용，기중，송순、백견목피순、홍삼순등기순단갑미류연생물적연구교위심입，본문중점대저사기순단갑미류연생물적생물활성、제취제비화개발응용등방면진행종술。
Inositol,a hexol widely found in nature with a wide range of physiological and biochemical effects,can promote fat metabolism in liver and other tissues and lower blood cholesterol and thus has been used for the clinical treatment of fatty liver, cirrhosis,atherosclerosis and hyperlipidemia. Some derivatives of inositol have been reported to have different biological activities including hypoglycemic,antitussive,anti-inflammatory and other effects. In recent years,its monomethyl ether derivatives,such as pinitol,quebrachitol,and sequoyiol,have been studied widely. In this paper,the bioactivity,extraction,preparation and applications of these monomethyl ether derivatives of inositol are reviewed.