现代中西医结合杂志
現代中西醫結閤雜誌
현대중서의결합잡지
MODERN JOURNAL OF INTEGRATED TRADITIONAL CHINESE AND WESTERN MEDICINE
2014年
32期
3535-3537,3540
,共4页
溃疡性结肠炎%生存质量%活动期%益生菌%气药灌肠%症状
潰瘍性結腸炎%生存質量%活動期%益生菌%氣藥灌腸%癥狀
궤양성결장염%생존질량%활동기%익생균%기약관장%증상
ulcerative colitis%quality of life%active stage%probiotic agentia%gas-pressured TCM UC enema%symptom
目的：探讨由益生菌口服、溃结灌肠液气药灌肠及5-ASA制剂与结肠炎丸口服组合成的3种阶梯式递减治疗方案对活动期溃疡性结肠炎患者生存质量的影响。方法将72例活动期溃疡性结肠炎患者随机等分为3组。试验组采用3种阶梯递减治疗方案，对照Ⅰ组较试验组减少益生菌口服，对照Ⅱ组再减少溃结灌肠液气药灌肠。每例患者治疗前后分别填写《炎症性肠病生存质量问卷》，并对结果进行统计学分析。结果试验组有效观察16例，对照Ⅰ组15例，对照Ⅱ组21例。与治疗前相比，各组生存质量均有提高（ P均＜0．05），且试验组优于对照组。结论3种治疗方案均可改善患者生存质量，试验组最优；但对照组病例脱落少，依从性较好；尤以对照Ⅱ组最为显著。试验组治疗获取不易及气液灌肠时的不适可能是患者依从性差的原因。
目的：探討由益生菌口服、潰結灌腸液氣藥灌腸及5-ASA製劑與結腸炎汍口服組閤成的3種階梯式遞減治療方案對活動期潰瘍性結腸炎患者生存質量的影響。方法將72例活動期潰瘍性結腸炎患者隨機等分為3組。試驗組採用3種階梯遞減治療方案，對照Ⅰ組較試驗組減少益生菌口服，對照Ⅱ組再減少潰結灌腸液氣藥灌腸。每例患者治療前後分彆填寫《炎癥性腸病生存質量問捲》，併對結果進行統計學分析。結果試驗組有效觀察16例，對照Ⅰ組15例，對照Ⅱ組21例。與治療前相比，各組生存質量均有提高（ P均＜0．05），且試驗組優于對照組。結論3種治療方案均可改善患者生存質量，試驗組最優；但對照組病例脫落少，依從性較好；尤以對照Ⅱ組最為顯著。試驗組治療穫取不易及氣液灌腸時的不適可能是患者依從性差的原因。
목적：탐토유익생균구복、궤결관장액기약관장급5-ASA제제여결장염환구복조합성적3충계제식체감치료방안대활동기궤양성결장염환자생존질량적영향。방법장72례활동기궤양성결장염환자수궤등분위3조。시험조채용3충계제체감치료방안，대조Ⅰ조교시험조감소익생균구복，대조Ⅱ조재감소궤결관장액기약관장。매례환자치료전후분별전사《염증성장병생존질량문권》，병대결과진행통계학분석。결과시험조유효관찰16례，대조Ⅰ조15례，대조Ⅱ조21례。여치료전상비，각조생존질량균유제고（ P균＜0．05），차시험조우우대조조。결론3충치료방안균가개선환자생존질량，시험조최우；단대조조병례탈락소，의종성교호；우이대조Ⅱ조최위현저。시험조치료획취불역급기액관장시적불괄가능시환자의종성차적원인。
Objective It is to explore the therapy by three stepwise decreasing different therapeutic schedules including probiotic agentia by oral use , gas-pressured TCM ulcerative colitis ( UC) enema and 5-ASA agentia with colitis pill by oral use on the quality of life ( QOL) in patients with active ulcerative colitis .Methods 72 cases of active UC patients were random divided into 3 groups, and 24 cases in each group.The test group was treated by the three stepwise decreasing different thera-peutic schedules ,control group Ⅰwas treated by the more brevity schedule which deleted probiotic agentia , and control groupⅡwas treated with orally 5-ASA agentia with colitis pill only .Inflammatory bowel diseases questionnaire ( IBDQ) should be filled by each patient before and after treatment , then the results were put into the database for statistical analysis .Resul ts 16 cases in treatment group , 15 cases in control group Ⅰand 21 cases in control group Ⅱ had been observed effectively .The scores were improved in all groups after treatment (P<0.05), and the improvements of the test group were better than that of the other two groups .Conclusion These three kinds of therapeutic schedules all could improve the QOL of active UC patients , and the effect in test group is better than others , but the obedience of patients in control group is better than that in test group because of lower case drain rate , especially in control group II , the effect is more significant .The difficulty about to get the clysis with gas-pressured TCM UC enema by an instrument ,and the discomfort caused by clysis maybe the reason why patients dislike the therapeutic schedules .
