CAJ | 학술논문

目的：研究活体非罪犯左主干病变的冠脉斑块成份与冠脉狭窄程度的相关性。方法2008年8月至2011年1月，共60例病患在亚洲大学医院被选为研究对象。经血管内超声（IVUS）确认血管直径狭窄大于或等于50％，同时为非罪犯左主干病例。应用血管内超声虚拟组织学软件（IVUS-VH）所得射频（RF）数据分析斑块成分。以 Gensini评分系统评定冠脉狭窄程度。评价成分与冠脉狭窄程度间的相关性。结果钙化组织面积和体积百分比与可体现冠脉狭窄程度的 Gensini评分呈正相关；坏死组织面积和体积百分比与可体现冠脉狭窄程度的 Gensini评分呈正相关。糖尿病组和非糖尿病组之间，对比不同冠脉斑块成分的平均组成比，结果差异无统计学意义（P＞0．05）。结论以 IVUS所得的 RF数据对斑块成分进行分析，利于确认成分与冠脉狭窄程度的相关性，可为临床治疗提供指导依据。
목적：연구활체비죄범좌주간병변적관맥반괴성빈여관맥협착정도적상관성。방법2008년8월지2011년1월，공60례병환재아주대학의원피선위연구대상。경혈관내초성（IVUS）학인혈관직경협착대우혹등우50％，동시위비죄범좌주간병례。응용혈관내초성허의조직학연건（IVUS-VH）소득사빈（RF）수거분석반괴성분。이 Gensini평분계통평정관맥협착정도。평개성분여관맥협착정도간적상관성。결과개화조직면적화체적백분비여가체현관맥협착정도적 Gensini평분정정상관；배사조직면적화체적백분비여가체현관맥협착정도적 Gensini평분정정상관。당뇨병조화비당뇨병조지간，대비불동관맥반괴성분적평균조성비，결과차이무통계학의의（P＞0．05）。결론이 IVUS소득적 RF수거대반괴성분진행분석，리우학인성분여관맥협착정도적상관성，가위림상치료제공지도의거。
Objective To study the correlation between nonculprit left main lesions′coronary plaque and severity of coronary ar-tery disease.Methods From August 2008 to January 2011,a total of 60 cases of patients in the Asian University Hospital were se-lected for the study.It was confirmed the vessel diameter stenosis≥ 50% by IVUS,meantime all patients were nonculprit left main lesions.RF data got from IVUS-Virtual Histology Software was used to analyze plaque components.Correlation between coronary stenosis and ingredients was evaluated by Gensini scoring system assessed coronary artery stenosis.Results Dense calcium(area and volume)percentages and Necrotic core(area and volume)percentages with the degree of coronary stenosis reflected Gensini score had positively correlation.Diabetic and non-diabetic group,respectively compared with an average of composition ratio of dif-ferent components of coronary plaque,the results were not statistically significant(P>0.05).Conclusion RF data obtained from IVUS plaque composition was analyzed,which will help confirm the composition and the correlation of coronary stenosis,and can provide guidance for clinical treatment.