CAJ | 학술논문

目的：观察不同剂量右美托咪定辅助用药对快通道全麻苏醒期的影响。方法：选择全麻患者90例，按入院时间随机分成A、B、C三组，三组分别以1、0.5、0.2μg/kg于麻醉前15 min静脉输注右美托咪定，后行全凭静脉麻醉。记录全麻期间各时间点血流动力学变化及苏醒期自主呼吸恢复时间、呼唤睁眼时间、拔管时间及并发症发生情况。结果：三组苏醒时间无差异(P>0.05)，A组在麻醉诱导前心率下降明显，苏醒期舌后坠，SPO2较低，C组苏醒期躁动发生率比B组高，比较差异均有统计学意义(P<0.05)。结论：0.5μg/kg右美托咪定辅助麻醉，血流动力学更稳定，对麻醉苏醒无影响且苏醒质量更高。
목적：관찰불동제량우미탁미정보조용약대쾌통도전마소성기적영향。방법：선택전마환자90례，안입원시간수궤분성A、B、C삼조，삼조분별이1、0.5、0.2μg/kg우마취전15 min정맥수주우미탁미정，후행전빙정맥마취。기록전마기간각시간점혈류동역학변화급소성기자주호흡회복시간、호환정안시간、발관시간급병발증발생정황。결과：삼조소성시간무차이(P>0.05)，A조재마취유도전심솔하강명현，소성기설후추，SPO2교저，C조소성기조동발생솔비B조고，비교차이균유통계학의의(P<0.05)。결론：0.5μg/kg우미탁미정보조마취，혈류동역학경은정，대마취소성무영향차소성질량경고。
Objective:To observe the effects of different doses dexmedtomidine of fast track anesthesia in the recovery of patients after general anesthesia. Method:90 cases of patients accepted general anesthesia,were randomly divide into 3 groups(group A、group B、group C),3 groups patients received dexmedetomidine 1,0.5,0.2μg/kg lasting for 15 min before general anesthesia,after total intravenous anesthesia,each time point during general anesthesia hemodynamic changes and the times of spontaneous breathing recovery,opening of eyes,extubation and side-effect were recorded.Result:There was no significant difference in waking time in the 3 groups (P>0.05).The patients of group A had significantly decreased heart rate before induction of anesthesia and lower SpO2 on the recovery(P<0.05).The incidence agitation in group C was higher than the group B(P<0.05).Conclusion:Supplemental anesthesia with 0.5μg/kg dexmedetomidine has a more stable hemodynamics,and a higher postoperative recovery quality,it does not affects the patients’ awaken period also.