中国现代医生
中國現代醫生
중국현대의생
CHINA MODERN DOCTOR
2014年
29期
143-145
,共3页
小儿支原体肺炎%阿奇霉素%序贯疗法%不良反应
小兒支原體肺炎%阿奇黴素%序貫療法%不良反應
소인지원체폐염%아기매소%서관요법%불량반응
Mycoplasma pneumonia%Azithromycin%Aequential therapy%Adverse reactions
目的：评价阿奇霉素序贯疗法用于小儿支原体肺炎治疗的疗效及安全性。方法选取2012年4月~2013年6月间于我院呼吸科就诊治疗的肺炎支原体感染患儿134例，按照治疗方式差异分为观察组和对照组，分别采用阿奇霉素序贯疗法及静脉滴注红霉素进行治疗，对比分析两组患儿的临床效果及不良反应发生情况。结果经14 d治疗后，观察组的治疗有效率为95.71%，较对照组(79.69%)显著升高(P<0.05)；观察组患儿咳嗽、发热、肺部湿啰音消失时间及住院时间均显著缩短(P<0.05)；同时，观察组的关节疼痛、皮疹、胃肠道反应、血清谷丙转氨酶升高的发生率均显著低于对照组(P<0.05)。结论采用阿奇霉素序贯疗法治疗小儿支原体肺炎，具有良好的临床疗效，显著缩短患儿的症状消失时间及住院时间，且毒副作用小，值得在临床广泛使用。
目的：評價阿奇黴素序貫療法用于小兒支原體肺炎治療的療效及安全性。方法選取2012年4月~2013年6月間于我院呼吸科就診治療的肺炎支原體感染患兒134例，按照治療方式差異分為觀察組和對照組，分彆採用阿奇黴素序貫療法及靜脈滴註紅黴素進行治療，對比分析兩組患兒的臨床效果及不良反應髮生情況。結果經14 d治療後，觀察組的治療有效率為95.71%，較對照組(79.69%)顯著升高(P<0.05)；觀察組患兒咳嗽、髮熱、肺部濕啰音消失時間及住院時間均顯著縮短(P<0.05)；同時，觀察組的關節疼痛、皮疹、胃腸道反應、血清穀丙轉氨酶升高的髮生率均顯著低于對照組(P<0.05)。結論採用阿奇黴素序貫療法治療小兒支原體肺炎，具有良好的臨床療效，顯著縮短患兒的癥狀消失時間及住院時間，且毒副作用小，值得在臨床廣汎使用。
목적：평개아기매소서관요법용우소인지원체폐염치료적료효급안전성。방법선취2012년4월~2013년6월간우아원호흡과취진치료적폐염지원체감염환인134례，안조치료방식차이분위관찰조화대조조，분별채용아기매소서관요법급정맥적주홍매소진행치료，대비분석량조환인적림상효과급불량반응발생정황。결과경14 d치료후，관찰조적치료유효솔위95.71%，교대조조(79.69%)현저승고(P<0.05)；관찰조환인해수、발열、폐부습라음소실시간급주원시간균현저축단(P<0.05)；동시，관찰조적관절동통、피진、위장도반응、혈청곡병전안매승고적발생솔균현저저우대조조(P<0.05)。결론채용아기매소서관요법치료소인지원체폐염，구유량호적림상료효，현저축단환인적증상소실시간급주원시간，차독부작용소，치득재림상엄범사용。
Objective To evaluate the efficacy and safety of azithromycin sequential therapy in treatment with my-coplasma pneumonia. Methods A total of 134 cases with mycoplasma pneumonia were selected in respiratory depart-ment of our hospital during April 2012 to June 2013, and then divided into observation group and control group ac-cording to the different treatment, which received azithromycin sequential therapy and erythromycin intravenous infu-sion respectively. The clinical effects and the incidence of adverse reactions were comparatively analyzed. Results 14 d after treatment,the treatment efficiency of observation group reached 95.71%,which was significantly higher than that in control (79.69%)(P<0.05).The fading time of coughing,the fading time of crackles and rale and the time of fever descending to normal were significantly shorter than that in control (P<0.05). Meanwhile,the adverse reaction rate of the observation group, include joint pain, rash, gastrointestinal reactions, elevated serum alanine aminotransferase,were significantly lower than that in the control group (P<0.05). Conclusion Azithromycin sequential therapy have a good clinical efficacy in treatment with mycoplasma pneumonia, shorten the symptoms disappearance time and hospi-talization time and reduce toxicity,which is widely used in clinical practice.
