CAJ | 학술논문

目的：分析昭通市各类疫苗预防接种异常反应(AEFI)的发生情况，评价各类疫苗的安全性和接种服务质量。方法通过全国AEFI监测系统收集昭通市2013年报告的AEFI病例，采用描述性流行病学方法进行分析。结果全市报告56例AEFI，其中一般反应32例(57.14%)，异常反应11例(19.64%)，偶合症3例(5.38%)，心因性反应2例(3.57%)，不明原因8例(14.29%)。报告发生不良反应的疫苗有8种，报告的总疑似异常反应发生率为1.7/10万，以卡介苗的发生率最高。在报告的预防接种不良反应中，以发热、接种部位红肿硬结出现等表现最为常见。结论通过实际工作接触发现，发生AEFI的因素很多，要改进疫苗制备纯度工艺，提高业务人员的自身综合素质，严格掌握疫苗禁忌证，规范接种流程能减少AEFI的发生。增强公众接种意识，从而提高全市预防接种水平。
목적：분석소통시각류역묘예방접충이상반응(AEFI)적발생정황，평개각류역묘적안전성화접충복무질량。방법통과전국AEFI감측계통수집소통시2013년보고적AEFI병례，채용묘술성류행병학방법진행분석。결과전시보고56례AEFI，기중일반반응32례(57.14%)，이상반응11례(19.64%)，우합증3례(5.38%)，심인성반응2례(3.57%)，불명원인8례(14.29%)。보고발생불량반응적역묘유8충，보고적총의사이상반응발생솔위1.7/10만，이잡개묘적발생솔최고。재보고적예방접충불량반응중，이발열、접충부위홍종경결출현등표현최위상견。결론통과실제공작접촉발현，발생AEFI적인소흔다，요개진역묘제비순도공예，제고업무인원적자신종합소질，엄격장악역묘금기증，규범접충류정능감소AEFI적발생。증강공음접충의식，종이제고전시예방접충수평。
Objective To analyze the AEFI causing by various vaccines and evaluate the safety of vaccine in Zhaotong, in order to provide a scientific strategy for reducing the incidence rate of AEFI and inoculation of servicial quality. Methods The AEFI data in 2013 were collected through the monitoring control system for AEFI in Zhaotong. The de-scriptive methodology is used in this study. Results The 56 AEFI cases were reported including 32 cases with general reaction(57.14%),11 cases with abnormal reaction (19.64%),3 cases with coincidental reaction (5.38%), 2 cases with psychogenic reaction (3.57%) and 8 cases with unknown reasons(14.29%). Adverse reactions were induced by 8 vaccines, and the total rate of suspected AEFI was 0.017‰ especially the BCG. The most commonly reported adverse events were fever, local reaction and partly callosity. Conclusion There are many factors of AEFI in practical works, and we should prepare purity process and improve the staff's comprehensive quality, strictly control of various vac-cines pre-vaccine contraindication. The standard vaccination process can reduce the incidence of AEFI. To enhance the public's awareness of vacaination, to improve the level of the city's vaccination.