CAJ | 학술논문

目的：探讨瑞芬太尼抑制子痫前期产妇气管插管心血管反应的半数有效浓度(EC50)。方法选择子痫前期产妇30例，静注拉贝洛尔后诱导，瑞芬太尼初始效应室浓度为3 ng/mL。气管插管心血管反应阳性标准院收缩压或舒张压≥160/110 mmHg。采用Probit概率回归法计算瑞芬太尼EC50及其95豫可信区间。结果瑞芬太尼抑制气管插管心血管反应的EC50及其95豫可信区间为1.93(1.89~1.95)ng/mL。结论瑞芬太尼抑制子痫前期产妇气管插管心血管反应的EC50为1.93 ng/mL。
목적：탐토서분태니억제자간전기산부기관삽관심혈관반응적반수유효농도(EC50)。방법선택자간전기산부30례，정주랍패락이후유도，서분태니초시효응실농도위3 ng/mL。기관삽관심혈관반응양성표준원수축압혹서장압≥160/110 mmHg。채용Probit개솔회귀법계산서분태니EC50급기95예가신구간。결과서분태니억제기관삽관심혈관반응적EC50급기95예가신구간위1.93(1.89~1.95)ng/mL。결론서분태니억제자간전기산부기관삽관심혈관반응적EC50위1.93 ng/mL。
Objective To determine the median effective concentration (EC50) of remifentanyl inhibiting cardiovascular response to tracheal intubation in women with preeclampsia. Methods Thirty women with preeclampsia were enrolled in this study. The target Ce was set at 3 ng/mL. The positive cardiovascular response was defined as the blood pressure≥160/110 mmHg. The EC50 (95%confidence interva1) of cardiovascular responses to tracheal intubation was calculated by Probit analysis. Results EC50 (95% confidence interval) of remifentanyl inhibiting cardiovascular response to tracheal intubation was 1.93 (1.89~1.95) ng/mL. Conclusion EC50 of remifentanyl inhibiting cardiovascular response to tracheal intubation is 1.93 ng/mL in women with preeclampsia.