CAJ | 학술논문

目的：运用X线胃钡餐动态摄影评价针刺治疗1个月前后功能性消化不良（ FD）患者胃动力与血清胃泌素及临床症状评分的变化及相互关系。方法根据罗马Ⅲ标准纳入17例FD患者，进行临床FD评分及胃钡餐动态摄影检查；其中8例接受针刺系统治疗1个月，治疗前后行胃钡餐动力检查、空腹血清胃泌素检测及症状评分。选择10例正常人作为对照组，接受以上相同的检测。胃钡餐动态摄影主要测量指标包括胃潴留液高度、蠕动波频率、蠕动波最大宽度、蠕动波最大深度、蠕动波通过时间、胃中间横带宽度。结果 FD患者与正常人胃潴留液高度、胃中间横带宽度、蠕动波频率、蠕动波通过时间比较均有显著性差异（P均＜＝0．01）。针刺治疗1个月后，FD患者单项及总体症状积分显著减低（P＜0．01），胃潴留液明显减少（P＜0．01），胃中间横带宽度缩小（P＜0．05），胃蠕动波频率加快（P＜0．01），胃蠕动波通过时间缩短（P＜0．05），血清胃泌素水平上升（P＜0．01），均趋向接近于正常人。在针灸治疗FD中，胃动力指数与症状指数及血清胃泌素水平变化具有一致性。结论 X线胃钡餐动态摄影可作为实用而价廉的FD胃动力检查方法，针刺治疗FD可能通过提高胃泌素水平、促进胃动力的提高而产生疗效。
목적：운용X선위패찬동태섭영평개침자치료1개월전후공능성소화불량（ FD）환자위동력여혈청위비소급림상증상평분적변화급상호관계。방법근거라마Ⅲ표준납입17례FD환자，진행림상FD평분급위패찬동태섭영검사；기중8례접수침자계통치료1개월，치료전후행위패찬동력검사、공복혈청위비소검측급증상평분。선택10례정상인작위대조조，접수이상상동적검측。위패찬동태섭영주요측량지표포괄위저류액고도、연동파빈솔、연동파최대관도、연동파최대심도、연동파통과시간、위중간횡대관도。결과 FD환자여정상인위저류액고도、위중간횡대관도、연동파빈솔、연동파통과시간비교균유현저성차이（P균＜＝0．01）。침자치료1개월후，FD환자단항급총체증상적분현저감저（P＜0．01），위저류액명현감소（P＜0．01），위중간횡대관도축소（P＜0．05），위연동파빈솔가쾌（P＜0．01），위연동파통과시간축단（P＜0．05），혈청위비소수평상승（P＜0．01），균추향접근우정상인。재침구치료FD중，위동력지수여증상지수급혈청위비소수평변화구유일치성。결론 X선위패찬동태섭영가작위실용이개렴적FD위동력검사방법，침자치료FD가능통과제고위비소수평、촉진위동력적제고이산생료효。
Objective It is to evaluate the changes of gastric motility, serum gastrin and clinical symptom scores after one month's treatment with acupuncture and their relationship in the patients with functional dyspepsia ( FD) by dynamic X-ray radiography with gastric barium meal .Methods Seventeen FD patients were selected according with the Rome III criteria , and their clinical FD scores were evaluated and received examination of dynamic X -ray radiography with barium meal , in which 8 cases were treated with acupuncture for 1 month and were given examination of dynamic X -ray radiography with barium meal , fasting serum gastrin measure and symptom score evaluation before and after treatment .10 normal people were selected as con-trol group and given the same examination .The imaging indexes of X -ray included the height of gastric retention liquid , the width of midgastric transverse band ( MTR) ,the frequency , width and depth of gastric slow waves .Results It showed signifi-cant differences between FD patients and healthy subjects in the imaging indexes of gastric motility including the height of gas -tric retention liquid,MTR,the frequency of stomach wave (P all <0.01).After one weeks'acupuncture in FD patients,single and total symptom scores were significantly decreased (P<0.01), gastric retention liquid and MTR were decreased (P<0.01 or P<0.05), frequency of gastric slow waves was fasted (P<0.01), propagation velocity of gastric slow waves was shortened (P<0.05), the level of serum gastrin was increaed (P<0.01).the outcomes showed these indexes were improved to the normal values closely .In the treatment with acupuncture for FD , gastric motility index was in accordance with the changes of symptom index and serum gastrin .Conclusion The dynamic X-ray radiography with gastric barium meal can be a practical and cheap diagnosis method in evaluating for gastric motility disorder in FD .Acupuncture could treat for FD may through in-creasing the level of serum gastrin and then enhancing the gastric motility .