国际儿科学杂志
國際兒科學雜誌
국제인과학잡지
INTERNATIONAL JOURNAL OF PEDIATRICS
2014年
1期
2-5
,共4页
宫内感染%胎儿炎症反应%早产%脑损伤
宮內感染%胎兒炎癥反應%早產%腦損傷
궁내감염%태인염증반응%조산%뇌손상
Intrauterine infection%Fetal inflammatory response%Preterm birth%Brain injury
宫内感染后胎儿炎症反应在早产及早产儿脑损伤中发挥重要作用.胎儿炎症反应表现为胎儿循环中前炎症细胞因子增加.炎症信号可通过血脑屏障启动胎儿神经炎症反应,导致发育中大脑损伤.全面理解胎儿炎症反应有助于提出干预措施并改善早产儿神经发育结局.该文就胎儿炎症反应与早产儿脑损伤相关问题作一综述.
宮內感染後胎兒炎癥反應在早產及早產兒腦損傷中髮揮重要作用.胎兒炎癥反應錶現為胎兒循環中前炎癥細胞因子增加.炎癥信號可通過血腦屏障啟動胎兒神經炎癥反應,導緻髮育中大腦損傷.全麵理解胎兒炎癥反應有助于提齣榦預措施併改善早產兒神經髮育結跼.該文就胎兒炎癥反應與早產兒腦損傷相關問題作一綜述.
궁내감염후태인염증반응재조산급조산인뇌손상중발휘중요작용.태인염증반응표현위태인순배중전염증세포인자증가.염증신호가통과혈뇌병장계동태인신경염증반응,도치발육중대뇌손상.전면리해태인염증반응유조우제출간예조시병개선조산인신경발육결국.해문취태인염증반응여조산인뇌손상상관문제작일종술.
The fetal inflammatory response to intrauterine infection plays a crucial role in the pathogenesis of preterm birth and preterm brain injury.The fetal inflammatory response is characterized by elevated levels of proinflammatory cytokines in the fetal circulation.The inflammation signal is likely transmitted across the blood-brain barrier and initiates a neuroinflammatory response and triggers damage in the developing brain.A better understanding of the fetal inflammatory response will help design interventions to improve neurodevelopmental outcomes after preterm birth.This review summarizes researches of fetal inflammatory response and brain injury in the preterm newborn.
