CAJ | 학술논문

以取代2-溴吡啶和羟基苯硼酸为原料，经Suzuki偶联和亲核取代两步反应合成了9个未见报道的含取代2-苯基吡啶基团的甲氧基氨基甲酸酯类化合物，其结构均经红外光谱、核磁共振氢谱及质谱( ESI-MS)表征。初步生物活性测定结果表明：在500 mg/L下，部分化合物对朱砂叶螨Tetranychus cinnabarinus的致死率达100％，具有作为杀螨剂先导结构的潜力。
이취대2-추필정화간기분붕산위원료，경Suzuki우련화친핵취대량보반응합성료9개미견보도적함취대2-분기필정기단적갑양기안기갑산지류화합물，기결구균경홍외광보、핵자공진경보급질보( ESI-MS)표정。초보생물활성측정결과표명：재500 mg/L하，부분화합물대주사협만Tetranychus cinnabarinus적치사솔체100％，구유작위살만제선도결구적잠력。
Nine novel methoxylcarbamates containing substituted 2-phenylpyridine moieties were synthesized from hydroxyphenylboronic acid and substituted 2-bromopyridine via Suzuki cross-coupling reaction and nucleophilic substitution sequence. Their structures were characterized by IR,1 H NMR and ESI-MS. The preliminary bioassay showed that some compounds exhibited excellent lethality against Tetranychus cinnabarinus at 500 mg/L. The results indicated that above methoxylcarbamates can serve as potential acaricidal lead compounds.