CAJ | 학술논문

研究了新型环烷基磺酰胺类化合物N-(2，4，5-三氯苯基)-2-氧代环己烷基磺酰胺(简称化合物108)对灰葡萄孢菌丝生长、孢子形成和萌发以及菌核产生等不同生育阶段的抑制作用及其对菌丝致病力和形态结构的影响。结果表明：化合物108对灰葡萄孢菌丝生长和孢子形成及孢子萌发具有明显的抑制作用，其EC50值分别为6.90、4.70和4.11μg/mL；菌核形成受到明显抑制，当药剂质量浓度达20μg/mL时，无菌核产生。经化合物108处理后的灰葡萄孢菌丝致病力下降，40μg/mL 处理的菌丝致病力显著低于对照。超微结构观察结果表明，化合物108能导致灰葡萄孢菌丝萎缩、塌陷和变形，菌体细胞壁增厚、皱缩及分层。
연구료신형배완기광선알류화합물N-(2，4，5-삼록분기)-2-양대배기완기광선알(간칭화합물108)대회포도포균사생장、포자형성화맹발이급균핵산생등불동생육계단적억제작용급기대균사치병력화형태결구적영향。결과표명：화합물108대회포도포균사생장화포자형성급포자맹발구유명현적억제작용，기EC50치분별위6.90、4.70화4.11μg/mL；균핵형성수도명현억제，당약제질량농도체20μg/mL시，무균핵산생。경화합물108처리후적회포도포균사치병력하강，40μg/mL 처리적균사치병력현저저우대조。초미결구관찰결과표명，화합물108능도치회포도포균사위축、탑함화변형，균체세포벽증후、추축급분층。
The antifungal activity of cycloalkyl sulfonylureas N-(2,4,5-trichlorophenyl)-2-oxocyclohexylsulfonamide ( compound 108 for short) against Botrytis cinerea was investigated in vitro. The results showed that compound 108 could inhibit different stages of B. cinerea including hyphal growth, spore production and germination, with EC50 values of 6. 90, 4. 70 and 4. 11 μg/mL, respectively. The sclerotic production and pathogenicity of B. cinerea could also be inhibited by compound 108, and the hyphal could not produce sclerotia under 20 μg/mL of the compound. The pathogenicity of B. cinerea mycelia treated by compound 108 at 40 μg/mL was significantly lower than that of the control. Morphological and ultrastructural studies showed that compound 108 could cause hyphae collapse, deforming, and cell wall shrinkage, thickening and layering of B. cinerea.