CAJ | 학술논문

病理性近视家系的致病基因之一LAMA1基因与层粘连蛋白有关，LAMA1基因编码层粘连蛋白的ɑ1链，其在维系层粘连蛋白结构和功能上起主要作用，层粘连蛋白在眼球巩膜中的表达与病理性近视的发展密切相关，本文就病理性近视和层粘连蛋白相关性研究进展进行综述。
병이성근시가계적치병기인지일LAMA1기인여층점련단백유관，LAMA1기인편마층점련단백적ɑ1련，기재유계층점련단백결구화공능상기주요작용，층점련단백재안구공막중적표체여병이성근시적발전밀절상관，본문취병이성근시화층점련단백상관성연구진전진행종술。
LAMA1 ( alpha subunit of laminin ) is one of the candidate genes responsible for pathological myopia .It plays a major role in maintaining the structure and function of laminin protein .Expression of laminin in sclera of the eyeball is closely related to the development of pathological myopia .This article reviews the research progress of relationship between pathological myopia and laminin .