CAJ | 학술논문

目的：探讨三磷酸腺苷（ ATP）对皮肤交感神经的影响。方法运动员90人，随机分为对照组、无菌水组和ATP组，以组别于小腿皮下注射无菌水1 mL或ATP 1 mL（0．1 mg），于力竭运动前后注射后3～5 min开始测试皮肤交感反应（SSR），测试记录点距离小腿注射点10 cm，测试指标：起始潜伏期、末梢潜伏期和波幅，并观察ATP皮肤交感神经兴奋的范围。结果力竭运动后对照组和无菌水组的SSR波幅与力竭运动前比较，均有明显下降（P＜0．05）。力竭运动前及力竭运动后ATP组SSR波幅均大于对照组和无菌水组，且差异有显著性意义（P＜0．05）。 ATP 1 mL（0．1 mg）对交感神经末梢跨节段兴奋范围达10 cm。结论小腿局部皮下注射ATP 1 mL（0．1 mg）能产生该区域皮肤交感神经兴奋作用，其兴奋作用有沿皮肤向外周扩散特征。
목적：탐토삼린산선감（ ATP）대피부교감신경적영향。방법운동원90인，수궤분위대조조、무균수조화ATP조，이조별우소퇴피하주사무균수1 mL혹ATP 1 mL（0．1 mg），우력갈운동전후주사후3～5 min개시측시피부교감반응（SSR），측시기록점거리소퇴주사점10 cm，측시지표：기시잠복기、말소잠복기화파폭，병관찰ATP피부교감신경흥강적범위。결과력갈운동후대조조화무균수조적SSR파폭여력갈운동전비교，균유명현하강（P＜0．05）。력갈운동전급력갈운동후ATP조SSR파폭균대우대조조화무균수조，차차이유현저성의의（P＜0．05）。 ATP 1 mL（0．1 mg）대교감신경말소과절단흥강범위체10 cm。결론소퇴국부피하주사ATP 1 mL（0．1 mg）능산생해구역피부교감신경흥강작용，기흥강작용유연피부향외주확산특정。
Objective To investigate the effect of ATP on skin sympathetic nerve .Methods Ninety athletes were randomly divided into control group , sterile water group and ATP group .The latter two groups received subcutaneous injection in the lower leg of sterile water 1 mL or ATP 1 mL (0.1 mg), respectively.SSR was tested 3-5 min after injection with the test point 10 cm to the injection site in the lower leg .Test index included onset latency , distal latency and amplitude .The skin sympathetic excitement range was measured .Results After exhaustive exercise , the amplitudes of SSR in control and sterile water groups were significantly decreased (P<0.05).The amplitude of SSR in ATP group was higher than those in control and sterile water groups (P<0.05) both before and after exhaustive exercise .ATP 1 mL(0.1 mg) excited sympathetic nerve endings cross section with a range up to 10 cm.Conclusion Lower leg subcutaneous injection of ATP 1 mL (0.1 mg) can produce skin sympathetic nerve excitement and its excitatory effects have characteristic diffusion along the skin .