CAJ | 학술논문

目的：地特胰岛素治疗妊娠糖尿病的疗效及安全性。方法：60例门诊妊娠糖尿病患者随机分为优泌林中效胰岛素组(对照组)和地特胰岛素组(治疗组)，所有病人均给予符合妊娠期要求的糖尿病教育及糖尿病饮食和运动，对照组使用优泌林中效胰岛素控制空腹血糖，治疗组使用地特胰岛素控制血糖，两组均为每晚睡前注射一次，两组均辅以餐时门冬胰岛素治疗，全部病例观察3个月。结果：治疗组与对照组相比有更高的治疗达标率，更好的空腹血糖和糖化血红蛋白水平，更少的夜间低血糖(P<0.05)。结论：地特胰岛素在治疗妊娠糖尿病较中效胰岛素更具有安全性和有效性。
목적：지특이도소치료임신당뇨병적료효급안전성。방법：60례문진임신당뇨병환자수궤분위우비림중효이도소조(대조조)화지특이도소조(치료조)，소유병인균급여부합임신기요구적당뇨병교육급당뇨병음식화운동，대조조사용우비림중효이도소공제공복혈당，치료조사용지특이도소공제혈당，량조균위매만수전주사일차，량조균보이찬시문동이도소치료，전부병례관찰3개월。결과：치료조여대조조상비유경고적치료체표솔，경호적공복혈당화당화혈홍단백수평，경소적야간저혈당(P<0.05)。결론：지특이도소재치료임신당뇨병교중효이도소경구유안전성화유효성。
Objective:To observe the clinical efficacy and safety of the gestational diabetes patients with insulin detemir treatment. Methods:Patients(60 cases) with gestational diabetes from May 2013 to January 2014 in Wangjiang Hospital of Sichuan University were randomly divided into treatment group(30 cases)and control group(30 cases). Each group was given a diet and insulin aspart therapy,while the control group with neutral protamine hagedorn( NPH) treatment and the treatment group with insulin detemir once-dai-ly to control the fasting blood sugar. After the treatment for three months,the two groups were compared with treatment compliance rate, fasting blood sugar,glycosylated hemglobin,and night hypoglycemia incidences. Results:The patients of pre-and post-treatment self-re-flection in the two groups had significant differences(P<0. 05);the improvement of fasting blood sugar,glycosylated hemglobin of pa-tients in the treatment group was superior to those in the control group which also had higher treatment compliance rate and less night hypoglycemia incidences(P<0. 05). Conclusion:It is showed that the insulin detemir treatment in gestational diabetes were more ef-fective and safe.