CAJ | 학술논문

大黄为临床常用药物，近年来，有关其毒性的报道越来越引起人们的关注，已成为亟待解决的重要问题。对近年来有关大黄肝毒性及其作用机制的研究进展予以全面综述，并结合中药配伍及组方原则提出了相应的减毒对策。为临床安全应用大黄和最终实现大黄的现代化和国际化提供参考依据。
대황위림상상용약물，근년래，유관기독성적보도월래월인기인문적관주，이성위극대해결적중요문제。대근년래유관대황간독성급기작용궤제적연구진전여이전면종술，병결합중약배오급조방원칙제출료상응적감독대책。위림상안전응용대황화최종실현대황적현대화화국제화제공삼고의거。
Rhubarb is widely used in Western Europe and Southeast Asia for a long time .In recent years , more and more reports about its toxicity cause for concern , which has become a world focus of discussion .In this paper , hepatic toxicity of rhubarb was reviewed .The cur-rent research provides a basis for safety evaluation and appropriate use of rhubarb .