中国计划生育和妇产科
中國計劃生育和婦產科
중국계화생육화부산과
CHINESE JOURNAL OF FAMILY PLANNING & GYNECOTOKOLOGY
2014年
7期
40-42,52
,共4页
输卵管性不孕%解脲支原体%人型支原体%药敏试验
輸卵管性不孕%解脲支原體%人型支原體%藥敏試驗
수란관성불잉%해뇨지원체%인형지원체%약민시험
tubal infertility%Ureaplasma urealyticum%Mycoplasma hominis%drug sensitivity test
目的：探讨支原体感染与输卵管性不孕的相关性及其药敏变迁，为指导临床合理用药提供参考。方法选择2011~2013年在广州市天河区人民医院妇产科就诊的输卵管性不孕患者345例为观察组，按年龄、职业、文化程度和营养状况1：1匹配正常孕妇345例为对照组，用微生物检验法，作支原体培养及药敏测定。结果观察组解脲支原体（ Ureaplasma urealyticum，Uu）、人型支原体（ Mycoplasma hominis，Mh）和Uu+Mh检出率（67.25%，8.12%，2.61%）均高于对照组（15.94%，1.74%，0.58%）（P<0.05）；观察组中138例输卵管完全阻塞患者与207例部分阻塞患者的 Uu、Mh和 Uu+Mh检出率差异无统计学意义（ P >0.05）；Uu对交沙霉素、美满霉素和强力霉素表现出较高较稳定的敏感性（88.78~78.95%）；Mh和Uu+Mh对美满霉素、交沙霉素和强力霉素均高度敏感（88.24%~90.91%）。结论生殖道支原体感染与不孕症具有相关性；监测其药敏及变迁有助于合理用药。
目的：探討支原體感染與輸卵管性不孕的相關性及其藥敏變遷，為指導臨床閤理用藥提供參攷。方法選擇2011~2013年在廣州市天河區人民醫院婦產科就診的輸卵管性不孕患者345例為觀察組，按年齡、職業、文化程度和營養狀況1：1匹配正常孕婦345例為對照組，用微生物檢驗法，作支原體培養及藥敏測定。結果觀察組解脲支原體（ Ureaplasma urealyticum，Uu）、人型支原體（ Mycoplasma hominis，Mh）和Uu+Mh檢齣率（67.25%，8.12%，2.61%）均高于對照組（15.94%，1.74%，0.58%）（P<0.05）；觀察組中138例輸卵管完全阻塞患者與207例部分阻塞患者的 Uu、Mh和 Uu+Mh檢齣率差異無統計學意義（ P >0.05）；Uu對交沙黴素、美滿黴素和彊力黴素錶現齣較高較穩定的敏感性（88.78~78.95%）；Mh和Uu+Mh對美滿黴素、交沙黴素和彊力黴素均高度敏感（88.24%~90.91%）。結論生殖道支原體感染與不孕癥具有相關性；鑑測其藥敏及變遷有助于閤理用藥。
목적：탐토지원체감염여수란관성불잉적상관성급기약민변천，위지도림상합리용약제공삼고。방법선택2011~2013년재엄주시천하구인민의원부산과취진적수란관성불잉환자345례위관찰조，안년령、직업、문화정도화영양상황1：1필배정상잉부345례위대조조，용미생물검험법，작지원체배양급약민측정。결과관찰조해뇨지원체（ Ureaplasma urealyticum，Uu）、인형지원체（ Mycoplasma hominis，Mh）화Uu+Mh검출솔（67.25%，8.12%，2.61%）균고우대조조（15.94%，1.74%，0.58%）（P<0.05）；관찰조중138례수란관완전조새환자여207례부분조새환자적 Uu、Mh화 Uu+Mh검출솔차이무통계학의의（ P >0.05）；Uu대교사매소、미만매소화강력매소표현출교고교은정적민감성（88.78~78.95%）；Mh화Uu+Mh대미만매소、교사매소화강력매소균고도민감（88.24%~90.91%）。결론생식도지원체감염여불잉증구유상관성；감측기약민급변천유조우합리용약。
Objective To explore the relationship between the reproductive tract infection of mycoplasma and tubal infertility and transition of drug sensitivity,to offer reference for clinical rational drug use. Methods 345 cases with tubal infertility in Tianhe District First Peopleˊs Hospital of Guangzhou City from 2011 to 2013 were selected as observation group,345 normal pregnant women matching to observation group according to age,occupation, cultural degree and nourishment condition were selected as control group. Mycoplasma culture and drug sensitivity were tested with microbiological test. Results The infectious rate of Ureaplasma urealyticum( Uu),Mycoplasma hominis(Mh)and Uu+Mh were 67. 25%,8. 12% and 2. 61% respectively in observation group,which were higher than control group(15. 94%,1. 74% and 0. 58%)(P<0. 05). However,the infectious rate of Uu,Mh and Uu+Mh in 138 cases with complete tubal obstruction showed no significant differences compared to 207 cases with partial tubal obstruction(P>0. 05). Josamycin,Minocycline and Doxycycline showed stable sensitivity to Uu(88. 78% ~78. 95%). Minocycline,Josamycin and Doxycycline showed high sensitivity to Mh and Uu + Mh( 88. 24% ~90. 91%)respectively. Conclusion Mycoplasma infection of reproductive tract has relation with tubal infertility, monitoring drug sensitivity of Mycoplasma is important for using medicine rationally.
