CAJ | 학술논문

目的：探讨不同时机肠内营养对重症急性胰腺炎（SAP）肠源性感染患者的临床疗效。方法将150例SAP肠源性感染患者采用随机数字表法分为两组，均进行常规基础治疗，同时治疗组（第1、2、3组）每组30例患者采用不同时机肠内营养支持治疗，对照组60例患者采用肠外营养支持治疗，并采用ApacheⅡ、BalthazarCT、Ranson评分系统评价四组患者的治疗效果。结果四组患者治疗后ApacheⅡ、BalthazarCT、Ranson评分均低于治疗前（P＝0.000），四组患者治疗前后ApacheⅡ评分比较差异具有显著性（F＝8.732，P＝0.016），第1组优于第2、3组及对照组，第2组优于第3组及对照组（P＜0.05）；四组患者治疗前后BalthazarCT评分比较差异具有显著性（F＝7.329，P＝0.011），第1组优于第2、3组及对照组，第2组优于第3组及对照组（P＜0.05）；四组患者治疗前后Ranson评分比较差异具有显著性（F＝6.389，P＝0.027），第1组优于第2、3组及对照组，第2组优于第3组及对照组（P＜0.05）。结论不同时机肠内营养支持治疗SAP可有效控制肠源性感染，加快患者恢复，且越早治疗效果越好。
목적：탐토불동시궤장내영양대중증급성이선염（SAP）장원성감염환자적림상료효。방법장150례SAP장원성감염환자채용수궤수자표법분위량조，균진행상규기출치료，동시치료조（제1、2、3조）매조30례환자채용불동시궤장내영양지지치료，대조조60례환자채용장외영양지지치료，병채용ApacheⅡ、BalthazarCT、Ranson평분계통평개사조환자적치료효과。결과사조환자치료후ApacheⅡ、BalthazarCT、Ranson평분균저우치료전（P＝0.000），사조환자치료전후ApacheⅡ평분비교차이구유현저성（F＝8.732，P＝0.016），제1조우우제2、3조급대조조，제2조우우제3조급대조조（P＜0.05）；사조환자치료전후BalthazarCT평분비교차이구유현저성（F＝7.329，P＝0.011），제1조우우제2、3조급대조조，제2조우우제3조급대조조（P＜0.05）；사조환자치료전후Ranson평분비교차이구유현저성（F＝6.389，P＝0.027），제1조우우제2、3조급대조조，제2조우우제3조급대조조（P＜0.05）。결론불동시궤장내영양지지치료SAP가유효공제장원성감염，가쾌환자회복，차월조치료효과월호。
Objective To study the clinical effect of different time application of enteral nutrition for patients with severe acute pancreatitis (SAP) enterogenic infection. Method 150 patients with SAP enterogenic infection were randomly divided into two groups, both groups for treatment on a regular basis, at the same time, the treatment group with different timing of enteral nutrition support treatment, control group adopted parenteral nutrition support treatment. Result After treatment the ApacheⅡ, BalthazarCT and Ranson score were lower than before treatment (P=0.000), before and after treatment, four groups of ApacheⅡscores were statistically difference (F=8.732, P=8.732), group 1 was better than that of group 2, 3 and control group, group 2 was superior to group 3 and control group (P<0.05);before and after the treatment, four groups BalthazarCT scores was statistically difference (F=7.329, P=7.329), group 1 was better than that of group 2, 3 and control group, group 2 was superior to group 3 and control group (P<0.05);before and after treatment, four groups of Ranson score was statistically difference (F=6.389, P=6.389), group 1 was better than that of group 2, 3 and control group, group 2 was superior to group 3 and control group (P<0.05). Conclusion Different time in patients with SAP, enteral nutrition support therapy can effectively control the enterogenic infection, to speed up the patients recover, and the earlier treatment begins the better the results.