中华老年多器官疾病杂志
中華老年多器官疾病雜誌
중화노년다기관질병잡지
CHINESE JOURNAL OF MULTIPLE ORGAN DISEASES IN THE ELDERLY
2014年
10期
792-795
,共4页
甲状腺乳头状微小癌%临床特点%BRAF基因%人类
甲狀腺乳頭狀微小癌%臨床特點%BRAF基因%人類
갑상선유두상미소암%림상특점%BRAF기인%인류
papillary thyroid microcarcinoma%clinical features%BRAF gene%human
甲状腺癌是最常见的内分泌系统恶性肿瘤，其中甲状腺乳头状癌（papillary thyroid carcinoma，PTC）占80%左右。甲状腺乳头状微小癌（papillary thyroid microcarcinoma，PTMC）是指直径≤1.0cm、无论有无淋巴结转移或远处转移的PTC。近年，随着甲状腺超声技术的不断发展和广泛应用，其临床检出率呈上升趋势。一般认为PTMC的恶性程度较低，总体预后良好。但也有文献报道在诊断PTMC的同时已发现存在区域淋巴结转移或远处转移。本文就PTMC的流行病学、临床生物学以及分子生物学特点作一综述。
甲狀腺癌是最常見的內分泌繫統噁性腫瘤，其中甲狀腺乳頭狀癌（papillary thyroid carcinoma，PTC）佔80%左右。甲狀腺乳頭狀微小癌（papillary thyroid microcarcinoma，PTMC）是指直徑≤1.0cm、無論有無淋巴結轉移或遠處轉移的PTC。近年，隨著甲狀腺超聲技術的不斷髮展和廣汎應用，其臨床檢齣率呈上升趨勢。一般認為PTMC的噁性程度較低，總體預後良好。但也有文獻報道在診斷PTMC的同時已髮現存在區域淋巴結轉移或遠處轉移。本文就PTMC的流行病學、臨床生物學以及分子生物學特點作一綜述。
갑상선암시최상견적내분비계통악성종류，기중갑상선유두상암（papillary thyroid carcinoma，PTC）점80%좌우。갑상선유두상미소암（papillary thyroid microcarcinoma，PTMC）시지직경≤1.0cm、무론유무림파결전이혹원처전이적PTC。근년，수착갑상선초성기술적불단발전화엄범응용，기림상검출솔정상승추세。일반인위PTMC적악성정도교저，총체예후량호。단야유문헌보도재진단PTMC적동시이발현존재구역림파결전이혹원처전이。본문취PTMC적류행병학、림상생물학이급분자생물학특점작일종술。
Thyroid cancer is the most common malignancy in endocrine system,and papillarythyroid carcinoma (PTC) accounts for about 80% of thyroid cancer. Papillarythyroidmicrocarcinoma (PTMC) refers to thePTCwith the diameter less than 1.0cm, with or without lymph nodes metastases or distant metastases.In recent years, with the rapid development and wide application of ultrasonic technology,its detection rate isin a trend ofincreasing. Generally, PTMC is considered to beinlower malignancy andwithgood prognosis. However, there are still some reportsindicating PTMC have been regional or distant metastasis in lymph nodes when PTMC is diagnosed. In this paper, we reviewedtheepidemiological, clinical, biological and molecular biological characteristics of PTMC.
