中国临床药理学杂志
中國臨床藥理學雜誌
중국림상약이학잡지
THE CHINESE JOURNAL OF CLINICAL PHARMACOLOGY
2014年
10期
962-965
,共4页
番茄红素%前列腺癌%作用机制%应用研究
番茄紅素%前列腺癌%作用機製%應用研究
번가홍소%전렬선암%작용궤제%응용연구
lycopene%prostate cancer%mechanism of action%utilization
番茄红素是一种天然的类胡萝卜素,主要存在于新鲜蔬菜和水果中,在番茄或番茄制品中含量最高;但目前番茄红素治疗前列腺癌的作用机制还未彻底阐明,动物研究及大型的临床随机试验有限,其预防和治疗前列腺癌的疗效仍缺乏临床证据。本文对番茄红素的生物学特性、抗前列腺癌的作用机制及其在前列腺癌的应用研究进展作一综述。
番茄紅素是一種天然的類鬍蘿蔔素,主要存在于新鮮蔬菜和水果中,在番茄或番茄製品中含量最高;但目前番茄紅素治療前列腺癌的作用機製還未徹底闡明,動物研究及大型的臨床隨機試驗有限,其預防和治療前列腺癌的療效仍缺乏臨床證據。本文對番茄紅素的生物學特性、抗前列腺癌的作用機製及其在前列腺癌的應用研究進展作一綜述。
번가홍소시일충천연적류호라복소,주요존재우신선소채화수과중,재번가혹번가제품중함량최고;단목전번가홍소치료전렬선암적작용궤제환미철저천명,동물연구급대형적림상수궤시험유한,기예방화치료전렬선암적료효잉결핍림상증거。본문대번가홍소적생물학특성、항전렬선암적작용궤제급기재전렬선암적응용연구진전작일종술。
Lycopene is a natural carotenoid mainly found in fresh vegeta -bles and fruits, among which tomatoes or tomato products possess the highest concentrations.However, currently the mechanism of the action for lycopene treating prostate cancer has not been completely elucidated and animal studies as well as large -scale randomized clinical trials re-main limited.Therefore, the efficacy of its prevention and treatment of prostate cancer still lacks clinical evidence.This article reviewed the bio-logical characteristics of lycopene , the mechanisms of its anti -prostate cancer and utilization progress.