CAJ | 학술논문

目的：分析青年女性冠心病患者冠状动脉病变特点及治疗方法。方法对≤40岁的女性冠心病患者的冠状动脉造影（CAG）特点进行分析，按造影结果分成零/单支病变组和多支病变组，进一步对临床表现、危险因素和治疗方法进行比较分析。结果共纳入78例患者。单支病变比例较高（43．6％）。零/单支病变组和多支病变组临床表现差异无统计学意义，均以心绞痛多见，分别占61．0％和64．9％，其次为心肌梗死，分别占29．3％和40．5％。传统危险因素合并比例高，高脂血症分别占63．4％和83．8％，多支病变组的2型糖尿病和高脂血症合并率均显著高于零/单支病变组（29．7％ vs 7．3％和83．8％ vs 63．4％， P 均＜0．05）。2型糖尿病是多支病变的独立危险因素。零/单支病变组的单纯药物治疗比例更高，而多支病变组的经皮冠状动脉介入（PCI）治疗更多。结论青年女性冠心病冠状动脉零支和单支病变较多，传统危险因素合并率高。
목적：분석청년녀성관심병환자관상동맥병변특점급치료방법。방법대≤40세적녀성관심병환자적관상동맥조영（CAG）특점진행분석，안조영결과분성령/단지병변조화다지병변조，진일보대림상표현、위험인소화치료방법진행비교분석。결과공납입78례환자。단지병변비례교고（43．6％）。령/단지병변조화다지병변조림상표현차이무통계학의의，균이심교통다견，분별점61．0％화64．9％，기차위심기경사，분별점29．3％화40．5％。전통위험인소합병비례고，고지혈증분별점63．4％화83．8％，다지병변조적2형당뇨병화고지혈증합병솔균현저고우령/단지병변조（29．7％ vs 7．3％화83．8％ vs 63．4％， P 균＜0．05）。2형당뇨병시다지병변적독립위험인소。령/단지병변조적단순약물치료비례경고，이다지병변조적경피관상동맥개입（PCI）치료경다。결론청년녀성관심병관상동맥령지화단지병변교다，전통위험인소합병솔고。
Objective To analyze the characters of coronary disease and treatment in young female with cornary heart disease .Methods Coronary angiography (CAG) results of young female patients with coronary disease (≤40 years old) were analyzed.They were divided into zero /one -vessel group and multi -vessel group according to CAG, and their clinical mani-festations, risk factors and treatment were compared between the two groups.Results Seventy -eight patients were enrolled.One -vessel lesion was the most common in CAG (43.6%).Clinical manifestations were basically similar in zero /one -vessel group and multi -vessel group:angina was the most common symptom in both groups ( 61.0% vs 64.9%), and the second common was myocardial infarction (29.3% vs 40.5%).Traditional risk factors were accompanied , such as hyperlipemia (63.4% vs 83.8%).Diabetes and hyperlipemia were more common in multi -vessel group than those in zero /one -vessel group (29.7% vs 7.3% and 83.8% vs 63.4%,P <0.05).Diabetes was an independent risk factor of multi -vessel lesions.Higher proportion of PCI in multi -vessel lesions and a higher proportion of single drug therapy in zero /one -vessel group were observed. Conclusion Zero/one vessel coronary lesions were common diseases in young females , in whom traditional risk factors also play an important role.