中国骨质疏松杂志
中國骨質疏鬆雜誌
중국골질소송잡지
CHINESE JOURNAL OF OSTEOPOROSIS
2014年
10期
1250-1253
,共4页
韩雨杉%伍雪%赵宏斌%钱传云
韓雨杉%伍雪%趙宏斌%錢傳雲
한우삼%오설%조굉빈%전전운
树鼩%骨代谢疾病%高脂血症%动脉粥样硬化%骨质疏松症
樹鼩%骨代謝疾病%高脂血癥%動脈粥樣硬化%骨質疏鬆癥
수구%골대사질병%고지혈증%동맥죽양경화%골질소송증
Tree shrew%Bone metabolic diseases%Hyperlipidemia%Atherosclerosis%Osteoporosis
高脂血症、动脉粥样硬化及骨质疏松症等代谢性疾病严重威胁人类健康。树鼩的形态、生理机能及生化代谢与人类极为相似,树鼩在脂代谢方面的独特之处可能成为其在研究代谢性疾病的明显优势。本文就近年来树鼩在代谢性疾病中应用的进展作一综述,旨在阐述各种代谢性疾病的树鼩模型,为骨代谢疾病的研究提供借鉴。
高脂血癥、動脈粥樣硬化及骨質疏鬆癥等代謝性疾病嚴重威脅人類健康。樹鼩的形態、生理機能及生化代謝與人類極為相似,樹鼩在脂代謝方麵的獨特之處可能成為其在研究代謝性疾病的明顯優勢。本文就近年來樹鼩在代謝性疾病中應用的進展作一綜述,旨在闡述各種代謝性疾病的樹鼩模型,為骨代謝疾病的研究提供藉鑒。
고지혈증、동맥죽양경화급골질소송증등대사성질병엄중위협인류건강。수구적형태、생리궤능급생화대사여인류겁위상사,수구재지대사방면적독특지처가능성위기재연구대사성질병적명현우세。본문취근년래수구재대사성질병중응용적진전작일종술,지재천술각충대사성질병적수구모형,위골대사질병적연구제공차감。
Metabolic diseases such as hyperlipoidemia, atherosclerosis, and osteoporosis have seriously threatened human health. The shape, physiological function and biochemical metabolism of the tree shrew are extremely similar to those of mankind.The distinctive property of the tree shrew in the lipid metabolism is likely to have obvious advantage in the research of metabolic diseases.This paper reviews the progresses the use of the tree shrew in metabolic diseases in recent years, aiming at demonstrating various types of metabolic diseases in tree shrew models, and further providing a reference for later research of bone metabolic diseases.