中国骨质疏松杂志
中國骨質疏鬆雜誌
중국골질소송잡지
CHINESE JOURNAL OF OSTEOPOROSIS
2014年
10期
1245-1249
,共5页
董万涛%吕泽斌%宋敏%柴居堂
董萬濤%呂澤斌%宋敏%柴居堂
동만도%려택빈%송민%시거당
骨枯髓空%骨质疏松症%神经-内分泌-免疫网络%分子机制%中药
骨枯髓空%骨質疏鬆癥%神經-內分泌-免疫網絡%分子機製%中藥
골고수공%골질소송증%신경-내분비-면역망락%분자궤제%중약
Marrow exhausted to bone wither%Osteoporosis%Nerve-endocrine-immune network%Molecular mechanism%Traditional Chinese medicine
对原发性骨质疏松症的病因病机进行归纳，阐述了“肾虚-骨枯髓空-骨痿”的病因病机特点及“骨枯髓空”与神经-内分泌-免疫网络的关系，将中医“肾主骨”理论与现代医学神经-内分泌-免疫网络有机结合探讨原发性骨质疏松症（骨痿）“骨枯髓空”的病机特点，以及运用补肾中药防治原发性骨质疏松症的作用机制，为中药防治原发性骨质疏松症提供客观的分子生物学和生物力学依据。
對原髮性骨質疏鬆癥的病因病機進行歸納，闡述瞭“腎虛-骨枯髓空-骨痿”的病因病機特點及“骨枯髓空”與神經-內分泌-免疫網絡的關繫，將中醫“腎主骨”理論與現代醫學神經-內分泌-免疫網絡有機結閤探討原髮性骨質疏鬆癥（骨痿）“骨枯髓空”的病機特點，以及運用補腎中藥防治原髮性骨質疏鬆癥的作用機製，為中藥防治原髮性骨質疏鬆癥提供客觀的分子生物學和生物力學依據。
대원발성골질소송증적병인병궤진행귀납，천술료“신허-골고수공-골위”적병인병궤특점급“골고수공”여신경-내분비-면역망락적관계，장중의“신주골”이론여현대의학신경-내분비-면역망락유궤결합탐토원발성골질소송증（골위）“골고수공”적병궤특점，이급운용보신중약방치원발성골질소송증적작용궤제，위중약방치원발성골질소송증제공객관적분자생물학화생물역학의거。
This review summarizes the pathogenesis of primary osteoporosis, explores the pathogenesis feature of kidney deficiency-marrow exhausted-bone wither-bone atrophy and the relationship with nerve-endocrine-immune network, and discusses pathogenic characteristics of primary osteoporosis ( bone atrophy ) combined with nerve-endocrine-immune network in modern medicine and the theory of kidney governing bone in Chinese medicine.It also provides an objective molecular biology and biomechanics basis for the prevention and treatment of primary osteoporosis, using the mechanism of kidney notifying medicine.
