CAJ | 학술논문

目的：探索复发性亚急性甲状腺炎治疗的新方法，了解甲状腺局部免疫治疗在复发性亚急性甲状腺炎中的应用有效性及安全性。方法选择门诊及住院42例糖皮质激素治疗后复发两次以上的亚急性甲状腺炎患者，以继续口服糖皮质激素和甲状腺局部免疫调节为中心的两种治疗方案治疗，比较两种治疗方法的疗效差异。结果对复发性亚急性甲状腺炎患者，甲状腺局部免疫调节治疗效果（总有效率为85．7％）优于继续口服激素治疗（总有效率为38．1％），差异有统计学意义（P＜0．05）。结论以甲状腺局部免疫调节为中心的综合治疗方案是复发性亚急性甲状腺炎治疗的一个新的探索，其疗效好，复发率低，不良反应少，值得推广。
목적：탐색복발성아급성갑상선염치료적신방법，료해갑상선국부면역치료재복발성아급성갑상선염중적응용유효성급안전성。방법선택문진급주원42례당피질격소치료후복발량차이상적아급성갑상선염환자，이계속구복당피질격소화갑상선국부면역조절위중심적량충치료방안치료，비교량충치료방법적료효차이。결과대복발성아급성갑상선염환자，갑상선국부면역조절치료효과（총유효솔위85．7％）우우계속구복격소치료（총유효솔위38．1％），차이유통계학의의（P＜0．05）。결론이갑상선국부면역조절위중심적종합치료방안시복발성아급성갑상선염치료적일개신적탐색，기료효호，복발솔저，불량반응소，치득추엄。
Objective To explore the new approach to he treatment of recurrent subacute thyroiditis.Methods The 42 outpatients and hospitalizations of subacute thyroiditis,recurrented after glucocorticoids treatment,were selected into two groups,using the two approach(con-tinue to oral glucocorticoids therapy,or thyroid local immune regulation therapy )to treat,and were compared the efficacy and safety between them.Results For the patients with recurrent subacute thyroiditis,the approach of thyroid local immune therapy is better than that of oral glucocorticoids therapy,including the efficacy and side effect,and there are significant difference between them (P<0.05).Conclusion The comprehensive treatment centered as thyroid local immune regulation therapy is a new exploration in the treatment of recurrent subacute thyroiditis,It was Worthy promoting for the better curative effect,lower recurrence rates and less adverse reactions.