CAJ | 학술논문

目的：探讨血清尿酸水平与急性脑梗死之间的相关性。方法：选择80例住院治疗的急性脑梗死患者(研究组)和同期体检(对照组)的79例健康体检者进行血清尿酸的检测,比较急性脑梗死患者和健康体检者的尿酸水平。将研究组患者依据尿酸水平分为高尿酸血症组和正常尿酸组,分别对其进行脑卒中量表( NIHSS)评分。结果：①脑梗死组患者和对照组健康体检者的空腹血清尿酸升高分别为47例和20例,血清尿酸分别为(438.5±78.9)μmol/L和(362.8±81.1)μmol/L,脑梗死组尿酸水平明显高于对照组,两组有显著性差异(P<0.01)；②高尿酸血症组患者的NIHSS评分高于正常尿酸组,差异具有统计学意义(P<0.05)；③血清尿酸水平与脑梗死患者病情及预后有平行关系。结论：尿酸水平是急性脑梗死的一个独立危险因素。
목적：탐토혈청뇨산수평여급성뇌경사지간적상관성。방법：선택80례주원치료적급성뇌경사환자(연구조)화동기체검(대조조)적79례건강체검자진행혈청뇨산적검측,비교급성뇌경사환자화건강체검자적뇨산수평。장연구조환자의거뇨산수평분위고뇨산혈증조화정상뇨산조,분별대기진행뇌졸중량표( NIHSS)평분。결과：①뇌경사조환자화대조조건강체검자적공복혈청뇨산승고분별위47례화20례,혈청뇨산분별위(438.5±78.9)μmol/L화(362.8±81.1)μmol/L,뇌경사조뇨산수평명현고우대조조,량조유현저성차이(P<0.01)；②고뇨산혈증조환자적NIHSS평분고우정상뇨산조,차이구유통계학의의(P<0.05)；③혈청뇨산수평여뇌경사환자병정급예후유평행관계。결론：뇨산수평시급성뇌경사적일개독립위험인소。
Objective:To study the relationship between the level of serum uric acid and acute cerebral infarction. Methods:The levels of uric acid were determined in 80 patients with acute cerebral infarction and compared with those of the corresponding 79 health controls. Then experimental group were divided into two groups by the levels of serum uric acid, one was high uric acid group, and the other was normal uric acid group. The NHISS score were made. Results: ①There were 47 cases in cerebral infarction group and 20 cases in health controls whose serum uric acid levels had increased. The mean levels of serum uric acid were 438. 5±78. 9 and 362. 8 ±81. 1, and the difference was statistically significant between the patients with acute cerebral infarction and the health controls (P<0. 01). ②The NHISS score of the high uric acid group was higher than that of the normal uric acid group, and the difference was statistically significant. ③The serum uric acid level had a parallel relationship with the condition and prognosis of the patients with cer-ebral infarction. Conclusions:High level of uric acid should be an independent risk factor for cerebral infarction.