CAJ | 학술논문

目的：明确儿童抗生素相关腹泻患儿下消化道病变，诊断和鉴别诊断儿童抗生素相关腹泻。方法对2013年6~9月18例经该院确诊为抗生素相关腹泻患儿进行纤维结肠镜检查。结果18例抗生素相关腹泻患儿中结肠镜检查表现为结肠黏膜弥漫性充血、水肿、血管分支模糊不清或消失14例，散在阿弗他溃疡、周围绕以红晕3例，散在糜烂溃疡及出血1例，未见假膜性肠炎表现。病变部位：乙状结肠及直肠9例，结肠脾曲及降结肠2例，横结肠3例，结肠肝曲及升结肠4例。18例患儿均行结肠黏膜活检术，镜下检查为非特异性炎性变化。结论儿童抗生素相关腹泻结肠镜检查表现均为非特异性炎性变化。儿童结肠镜检查安全、快速，在儿童抗生素相关腹泻的诊断及鉴别诊断中具有十分重要的作用，值得推广应用。
목적：명학인동항생소상관복사환인하소화도병변，진단화감별진단인동항생소상관복사。방법대2013년6~9월18례경해원학진위항생소상관복사환인진행섬유결장경검사。결과18례항생소상관복사환인중결장경검사표현위결장점막미만성충혈、수종、혈관분지모호불청혹소실14례，산재아불타궤양、주위요이홍훈3례，산재미란궤양급출혈1례，미견가막성장염표현。병변부위：을상결장급직장9례，결장비곡급강결장2례，횡결장3례，결장간곡급승결장4례。18례환인균행결장점막활검술，경하검사위비특이성염성변화。결론인동항생소상관복사결장경검사표현균위비특이성염성변화。인동결장경검사안전、쾌속，재인동항생소상관복사적진단급감별진단중구유십분중요적작용，치득추엄응용。
Objective To define the changes of the gastrointestinal tract of antibiotic-associated diarrhea(AAD) in chil-dren,diagnose and differentiate antibiotic-associated diarrhea in children. Methods Eighteen children,who were diagnosed with antibiotic-associated diarrhea were examined by fiber colonoscopy from June to September of 2013. Results 18 AAD children showed diffuse edema of colonic mucosa,vascular branching blurred or disappeared in 14 cases,scattered aphthous ulcers around to flush in 3 cases,scattered in 1 case of bleeding ulcers and erosions,no pseudomembranous colitis performance. Lesions:the sigmoid colon and rectum in 9 cases,splenic flexure and descending colon in 2 cases,transverse colon in 3 cases,hepatic flexure of colon and ascending colon in 4 cases. 18 children with AAD all underwent colonic mucosa biopsy with endoscopic non-specific inflammatory changes. Conclusion Colonoscopy performance of AAD children are non-specific inflammatory changes. Children colonoscopy is safe and fast,and it has a very important role in the diagnosis and differential diagnosis of AAD in children,which is worthy of promotion.