现代医药卫生
現代醫藥衛生
현대의약위생
MODERN MEDICINE HEALTH
2014年
20期
3056-3057,3060
,共3页
血液灌注%血液透析滤过%高磷血症/治疗%甲状旁腺素
血液灌註%血液透析濾過%高燐血癥/治療%甲狀徬腺素
혈액관주%혈액투석려과%고린혈증/치료%갑상방선소
Hemoperfusion%Hemodiafiltration%Hyperphosphatemia/therapy%Parathyroid hormone
目的：观察2种不同血液净化方式对维持性血液透析患者高血钙、高血磷、高血清甲状旁腺激素、皮肤瘙痒的改善效果。方法选择该院2012年4月至2013年4月进行维持性血液透析且病情稳定患者18例，随机分为单一组和联合组，各9例；单一组采用血液透析滤过（HDF）治疗，联合组采用血液透析（HD）联合血液灌流（HP）治疗。分别在治疗前及治疗后2周检查患者血钙、血磷、钙磷乘积和全段甲状旁腺激素（iPTH）。结果治疗2周后两组患者血钙均有所上升，血磷、iPTH均有所下降，与治疗前比较，差异均有统计学意义（P<0.05）；此外，联合组患者血磷及iPTH清除率均明显大于单一组，差异均有统计学意义（P<0.05）。结论 HDF和HD联合HP均能有效清除血磷和iPTH，但HD联合HP更有效。
目的：觀察2種不同血液淨化方式對維持性血液透析患者高血鈣、高血燐、高血清甲狀徬腺激素、皮膚瘙癢的改善效果。方法選擇該院2012年4月至2013年4月進行維持性血液透析且病情穩定患者18例，隨機分為單一組和聯閤組，各9例；單一組採用血液透析濾過（HDF）治療，聯閤組採用血液透析（HD）聯閤血液灌流（HP）治療。分彆在治療前及治療後2週檢查患者血鈣、血燐、鈣燐乘積和全段甲狀徬腺激素（iPTH）。結果治療2週後兩組患者血鈣均有所上升，血燐、iPTH均有所下降，與治療前比較，差異均有統計學意義（P<0.05）；此外，聯閤組患者血燐及iPTH清除率均明顯大于單一組，差異均有統計學意義（P<0.05）。結論 HDF和HD聯閤HP均能有效清除血燐和iPTH，但HD聯閤HP更有效。
목적：관찰2충불동혈액정화방식대유지성혈액투석환자고혈개、고혈린、고혈청갑상방선격소、피부소양적개선효과。방법선택해원2012년4월지2013년4월진행유지성혈액투석차병정은정환자18례，수궤분위단일조화연합조，각9례；단일조채용혈액투석려과（HDF）치료，연합조채용혈액투석（HD）연합혈액관류（HP）치료。분별재치료전급치료후2주검사환자혈개、혈린、개린승적화전단갑상방선격소（iPTH）。결과치료2주후량조환자혈개균유소상승，혈린、iPTH균유소하강，여치료전비교，차이균유통계학의의（P<0.05）；차외，연합조환자혈린급iPTH청제솔균명현대우단일조，차이균유통계학의의（P<0.05）。결론 HDF화HD연합HP균능유효청제혈린화iPTH，단HD연합HP경유효。
Objective To observe the effect of two different blood purification ways[hemodiafiltration(HDF),hemodialysis with hemoperfusion(HD with HP)] on hypocalcemia,hyperphosphatemia,high serum parathyroid hormone and pruritus improvement of patients with maintance hemodialysis. Methods A total of 18 patients with maintance hemodialysis and stable disease from April 2012 to April 2013 were selected and randomized into single group and combination group ,9 cases in each group. The sin-gle group used HDF for treatment,while the combination group adopted HD with HP for treatment. Before treatment and 2 weeks after treatment,the blood calcium,blood phosphorus,calcium-phosphorus product and intact parathyroid hormone(iPTH) were checked respectively. Results After 2 weeks of treatment,toth groups had an increase of blood calcium,while blood phosphorus and iPTH were decreased,and compared with the condition before treatment,the differences were statistically significant(P<0.05). In addition,blood phosphorus and iPTH clearance rate of combination group was obviously greater than those of the single group with statistically significant difference(P<0.05). Conclusion HDF and HP combined with HD can effectively remove blood phosphorus and iPTH,but the HP with HD has better effect.
