现代医药卫生
現代醫藥衛生
현대의약위생
MODERN MEDICINE HEALTH
2014年
20期
3053-3055
,共3页
冠状动脉疾病%针刺%胆囊切除术,腹腔镜
冠狀動脈疾病%針刺%膽囊切除術,腹腔鏡
관상동맥질병%침자%담낭절제술,복강경
Coronary disease%Acupuncture%Cholecystectomy,laparoscopic
目的:观察全身麻醉辅助针刺对冠状动脉粥样硬化性心脏病(冠心病)患者行腹腔镜胆囊摘除术时心肌应激反应的影响。方法将2011年2月至2013年12月择期行腹腔镜胆囊摘除术并确诊为冠心病的60例患者随机均分为全身麻醉组(A组)和全身麻醉辅助针刺组(B组),各30例。美国麻醉医师协会(ASA)分级Ⅱ级或Ⅲ级。A组采用咪唑安定、芬太尼、依托咪酯和维库溴铵麻醉诱导,麻醉维持采用丙泊酚、雷米芬太尼和维库溴铵;B组取内关、足三里穴持续刺激30min后进行全身麻醉诱导,麻醉诱导及维持与A组相同,针刺辅助持续至手术结束。记录两组患者麻醉前(T1),麻醉后20min(T2)、30min(T3)、45min(T4)及手术结束30min(T5)的血流动力学,T1、T3、T5时的心电图ST段变化。检测T1、T3时的血气分析,T1、T5时的肌酸激酶(CK)、乳酸脱氢酶(LDH)和心肌肌钙蛋白T(cTnT)等变化。结果T2、T3时两组患者心率明显增快、平均动脉压(MAP)明显升高,T2~T4时A组患者MAP明显高于B组,差异均有统计学意义(P<0.05)。T5时A组患者CK、LDH、cTnT较T1时明显升高,差异均有统计意义(P<0.05);B组患者CK、LDH、cTnT较T1时虽有所上升,但差异均无统计学意义(P>0.05);A组与B组上述指标比较,差异均有统计学意义(P<0.05)。A组患者术中需用硝酸甘油12例(40.0%)、艾司洛尔8例(26.7%),明显多于B组的6例(20.0%)和2例(6.7%)。结论全身麻醉辅助针刺用于冠心病患者行腹腔镜胆囊摘除术可在一定程度上起到对心肌的保护作用。
目的:觀察全身痳醉輔助針刺對冠狀動脈粥樣硬化性心髒病(冠心病)患者行腹腔鏡膽囊摘除術時心肌應激反應的影響。方法將2011年2月至2013年12月擇期行腹腔鏡膽囊摘除術併確診為冠心病的60例患者隨機均分為全身痳醉組(A組)和全身痳醉輔助針刺組(B組),各30例。美國痳醉醫師協會(ASA)分級Ⅱ級或Ⅲ級。A組採用咪唑安定、芬太尼、依託咪酯和維庫溴銨痳醉誘導,痳醉維持採用丙泊酚、雷米芬太尼和維庫溴銨;B組取內關、足三裏穴持續刺激30min後進行全身痳醉誘導,痳醉誘導及維持與A組相同,針刺輔助持續至手術結束。記錄兩組患者痳醉前(T1),痳醉後20min(T2)、30min(T3)、45min(T4)及手術結束30min(T5)的血流動力學,T1、T3、T5時的心電圖ST段變化。檢測T1、T3時的血氣分析,T1、T5時的肌痠激酶(CK)、乳痠脫氫酶(LDH)和心肌肌鈣蛋白T(cTnT)等變化。結果T2、T3時兩組患者心率明顯增快、平均動脈壓(MAP)明顯升高,T2~T4時A組患者MAP明顯高于B組,差異均有統計學意義(P<0.05)。T5時A組患者CK、LDH、cTnT較T1時明顯升高,差異均有統計意義(P<0.05);B組患者CK、LDH、cTnT較T1時雖有所上升,但差異均無統計學意義(P>0.05);A組與B組上述指標比較,差異均有統計學意義(P<0.05)。A組患者術中需用硝痠甘油12例(40.0%)、艾司洛爾8例(26.7%),明顯多于B組的6例(20.0%)和2例(6.7%)。結論全身痳醉輔助針刺用于冠心病患者行腹腔鏡膽囊摘除術可在一定程度上起到對心肌的保護作用。
목적:관찰전신마취보조침자대관상동맥죽양경화성심장병(관심병)환자행복강경담낭적제술시심기응격반응적영향。방법장2011년2월지2013년12월택기행복강경담낭적제술병학진위관심병적60례환자수궤균분위전신마취조(A조)화전신마취보조침자조(B조),각30례。미국마취의사협회(ASA)분급Ⅱ급혹Ⅲ급。A조채용미서안정、분태니、의탁미지화유고추안마취유도,마취유지채용병박분、뢰미분태니화유고추안;B조취내관、족삼리혈지속자격30min후진행전신마취유도,마취유도급유지여A조상동,침자보조지속지수술결속。기록량조환자마취전(T1),마취후20min(T2)、30min(T3)、45min(T4)급수술결속30min(T5)적혈류동역학,T1、T3、T5시적심전도ST단변화。검측T1、T3시적혈기분석,T1、T5시적기산격매(CK)、유산탈경매(LDH)화심기기개단백T(cTnT)등변화。결과T2、T3시량조환자심솔명현증쾌、평균동맥압(MAP)명현승고,T2~T4시A조환자MAP명현고우B조,차이균유통계학의의(P<0.05)。T5시A조환자CK、LDH、cTnT교T1시명현승고,차이균유통계의의(P<0.05);B조환자CK、LDH、cTnT교T1시수유소상승,단차이균무통계학의의(P>0.05);A조여B조상술지표비교,차이균유통계학의의(P<0.05)。A조환자술중수용초산감유12례(40.0%)、애사락이8례(26.7%),명현다우B조적6례(20.0%)화2례(6.7%)。결론전신마취보조침자용우관심병환자행복강경담낭적제술가재일정정도상기도대심기적보호작용。
Objective To observe the influence of acupuncture assisted with general anesthesia on cardiac stress reac-tion of patients with coronary heart underwent laparoscopic cholecystectomy. Methods Sixty ASAⅡorⅢpatients scheduled for elective laparoscopic cholecystectomy surgery from February 2011 to December 2013 were randomly divided into two groups:gen-eral aneasthesia(group A) and general aneasthesia combined with acupuncture(group B). Both groups were induced with midazo-lam,fentanyl,etomidate and vecuronium,and maitained with propofol,remifentanil and vecuronium,but the group B acupunc-tured to "zusanli" and "neiguan" for 30 min before anesthesia and lasted to operation over. Hemodynamics before anesthesia (T1),20 min(T2),30 min(T3),45 min(T4) after anesthesia and 30 min after operation(T5),and the changes of ECG in T1,T3,T5 were recorded. The blood gas analysis at T1 and T3,the changes of creatine kinase(CK),lactate dehydrogenase(LDH) and cTn-T were recorded. Results The heart rate(HR) and mean arterial pressure(MAP) of patients in both groups at T2 and T3 increased obviously,the MAP during T2 to T4 in the group A was obviously higher than that in the group B with statistically significant differ-ence(P<0.05);compared with T1,CK,LDH and cTn-T in the group B increased slightly,but the difference had no statisticaly sig-nificance(P>0.05);the difference between the two groups had statistical significance(P<0.05). 12 cases(40.0%) in the group A needed nitroglycerin and 8 cases(26.7%) needed esmolol,which was significantly higher than those in the group B[6(20.0%),2 (6.7%)] respectively. Conclusion The general aneasthesia combined with acupuncture in laparoscopic cholecystectomy of coro-nary heart disease can provide protection for myocardium to a certain.