CAJ | 학술논문

目的：探讨香砂六君子汤对胃癌患者免疫功能的影响，为胃癌的中医治疗提供临床依据。方法：收集胃癌患者95例，按抽签法分为治疗组（n＝48）和对照组（n＝47）。对照组仅采用FOLFOX 4的系统化疗方案治疗。治疗组采用香砂六君子汤治疗。比较两组患者术后治疗前后的细胞免疫功能指标及生存质量的变化情况。结果：两组治疗前比较，CD3＋、CD4＋、CD8＋、CD4＋/CD8＋无明显差异，治疗后，治疗组 CD3＋、CD4＋、CD4＋/CD8＋明显高于对照组（P<0.05），对照组治疗后CD8＋明显高于治疗前（P<0.05）；治疗后，治疗组生存质量改善达有效的比例明显高于对照组，差异有统计学意义（P<0.05）。结论：香砂六君子汤治疗对胃癌患者术后免疫功能具有明显的改善作用，有利于提高患者的生存质量，从而改善预后，值得临床借鉴。
목적：탐토향사륙군자탕대위암환자면역공능적영향，위위암적중의치료제공림상의거。방법：수집위암환자95례，안추첨법분위치료조（n＝48）화대조조（n＝47）。대조조부채용FOLFOX 4적계통화료방안치료。치료조채용향사륙군자탕치료。비교량조환자술후치료전후적세포면역공능지표급생존질량적변화정황。결과：량조치료전비교，CD3＋、CD4＋、CD8＋、CD4＋/CD8＋무명현차이，치료후，치료조 CD3＋、CD4＋、CD4＋/CD8＋명현고우대조조（P<0.05），대조조치료후CD8＋명현고우치료전（P<0.05）；치료후，치료조생존질량개선체유효적비례명현고우대조조，차이유통계학의의（P<0.05）。결론：향사륙군자탕치료대위암환자술후면역공능구유명현적개선작용，유리우제고환자적생존질량，종이개선예후，치득림상차감。
Objective: To investigate clinical effects of the Xiangsha Liujunzi decoction on immune function of gastric cancer patients. Methods:95 patients were randomly divided into two groups;the control group was given chemotherapy treatment, and another was given the Xiangsha Liujunzi decoction. Results:Compared with before treatment, CD3+, CD4+, CD4+/CD8+in the treatment group were significantly higher (P<0.05);CD8+in the control was significantly higher than before (P<0.05);the improvement of the quality of life in treatment group was obviously better, the difference was statistically significant (P<0.05). Conclusion: The Xiangsha Liujunzi decoction was effective on improving immune function, quality of life and the prognosis in patients, and is worthy of clinical reference.