CAJ | 학술논문

目的：研究aMi后nt-proBnP水平的变化对心功能不全的诊断及预测价值。方法选取96例初发aMi患者进行分析，记录24h内患者的心功能Killip分级等项目，并测定血浆nt-proBnP浓度。结果根据心功能Killip分级的各组的nt-proBnP浓度均随着级别的升高而增加，nt-proBnP和lnnt-proBnP随着心功能的减退而显著升高，差别有统计学意义（P＜0.01）。结论血浆中nt-proBnP在aMi后心功能不全的高危患者中显著升高，与急性期心功能Killip分级有明显联系，可以用于aMi后心功能不全的早期诊断及预测。
목적：연구aMi후nt-proBnP수평적변화대심공능불전적진단급예측개치。방법선취96례초발aMi환자진행분석，기록24h내환자적심공능Killip분급등항목，병측정혈장nt-proBnP농도。결과근거심공능Killip분급적각조적nt-proBnP농도균수착급별적승고이증가，nt-proBnP화lnnt-proBnP수착심공능적감퇴이현저승고，차별유통계학의의（P＜0.01）。결론혈장중nt-proBnP재aMi후심공능불전적고위환자중현저승고，여급성기심공능Killip분급유명현련계，가이용우aMi후심공능불전적조기진단급예측。
Objective to study the diagnosis and predictive value of nt- proBnP in cardiac insufficiency after acute myocardial infarction.Methods 96 cases of incipient acute myocardial infarction patients selected were analyzed and the patients' Killip classification of heart function within 24 h were recorded. and plasma nt - proBnP concentration were measured.Results NT-proBNP concentration increased with the rising grade according to the Killip classiifcation for cardiac function, and the level of nt- proBnP and lnnt- proBnP increased with heart function declining, the difference was statistically signiifcant (P<0.01).Conclusion The concentration of plasma NT-proBNP increased signiifcantly in high risk patients after acute myocardial infarction with cardiac insufifciency, and it has a signiifcant association with acute cardiac Killip classiifcation. Therefore, NT-proBNP can be used in diagnosis and prediction in patients with cardiac insufifciency after acute myocardial infarction.