中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2014年
29期
1-3
,共3页
平抵胶囊%代谢综合征%胰岛素抵抗
平牴膠囊%代謝綜閤徵%胰島素牴抗
평저효낭%대사종합정%이도소저항
The Pingdi capsule%Metabolism syndrome%Insulin resistance
目的：探讨益气活血法对代谢综合征胰岛素抵抗的影响及其部分作用机制。方法：将60例代谢综合征胰岛素抵抗患者随机分为两组，治疗组用自制“平抵胶囊”配合西药常规治疗，对照组单纯用西药常规治疗；观察治疗前后患者空腹血糖，血脂，胰岛素抵抗变化。结果：治疗后对照组总有效率为56.6%，治疗组为74.1%，两组患者治疗后总有效率比较有显著性差异（P<0.05）。两组患者治疗后FPG，FINS，TG，TC水平明显下降，与治疗前比较有显著性差异（P<0.05，P<0.01），治疗后组间比较也有显著性差异（P<0.05，P<0.01）；两组患者治疗后HDL-C水平均有升高，治疗组治疗前后比较有统计学差异（P<0.05），对照组治疗前后比较无统计学差异，治疗后两组间比较也无统计学差异。对照组治疗前后IR值无明显改善，与本组对照其差异无统计学意义，治疗组IR值明显改善，与对照组相比其差异有显著性统计学意义，P<0.01。结论：以益气活血法为主的自拟“平抵胶囊”对代谢综合征胰岛素抵抗患者具有较好疗效。
目的：探討益氣活血法對代謝綜閤徵胰島素牴抗的影響及其部分作用機製。方法：將60例代謝綜閤徵胰島素牴抗患者隨機分為兩組，治療組用自製“平牴膠囊”配閤西藥常規治療，對照組單純用西藥常規治療；觀察治療前後患者空腹血糖，血脂，胰島素牴抗變化。結果：治療後對照組總有效率為56.6%，治療組為74.1%，兩組患者治療後總有效率比較有顯著性差異（P<0.05）。兩組患者治療後FPG，FINS，TG，TC水平明顯下降，與治療前比較有顯著性差異（P<0.05，P<0.01），治療後組間比較也有顯著性差異（P<0.05，P<0.01）；兩組患者治療後HDL-C水平均有升高，治療組治療前後比較有統計學差異（P<0.05），對照組治療前後比較無統計學差異，治療後兩組間比較也無統計學差異。對照組治療前後IR值無明顯改善，與本組對照其差異無統計學意義，治療組IR值明顯改善，與對照組相比其差異有顯著性統計學意義，P<0.01。結論：以益氣活血法為主的自擬“平牴膠囊”對代謝綜閤徵胰島素牴抗患者具有較好療效。
목적：탐토익기활혈법대대사종합정이도소저항적영향급기부분작용궤제。방법：장60례대사종합정이도소저항환자수궤분위량조，치료조용자제“평저효낭”배합서약상규치료，대조조단순용서약상규치료；관찰치료전후환자공복혈당，혈지，이도소저항변화。결과：치료후대조조총유효솔위56.6%，치료조위74.1%，량조환자치료후총유효솔비교유현저성차이（P<0.05）。량조환자치료후FPG，FINS，TG，TC수평명현하강，여치료전비교유현저성차이（P<0.05，P<0.01），치료후조간비교야유현저성차이（P<0.05，P<0.01）；량조환자치료후HDL-C수평균유승고，치료조치료전후비교유통계학차이（P<0.05），대조조치료전후비교무통계학차이，치료후량조간비교야무통계학차이。대조조치료전후IR치무명현개선，여본조대조기차이무통계학의의，치료조IR치명현개선，여대조조상비기차이유현저성통계학의의，P<0.01。결론：이익기활혈법위주적자의“평저효낭”대대사종합정이도소저항환자구유교호료효。
Objective: To investigate clinical efficacy of Yiqi Huoxue therapy on insulin resistance of metabolism syndrome. Methods: 60 patients were randomly divided into two groups, the treatment group received Pingdi capsule plus western medicine; the control group was given western medicine solo. FPG, blood lipid, insulin resistance in both were observed before and after treatment. Results: The total efficiency in the control was 56.6%, in another was 74.1%after treatment. The difference was statistically significant (P<0.05). FPG, FINS, TG, TC in both were decreased after treatment, there were significant differences compared with those before and after treatment (P<0.05, P<0.01). HDL-C in both was improved, there were significant differences in the treatment group before and after treatment (P<0.05). There was no significant difference in the treatment group before and after treatment. Comparisons between two groups were no significant difference after treatment. IR was not improved in the control before and after treatment, there was no significant difference;IR was improved in the treatment, there was significant difference compared with the control group (P<0.01). Conclusion:The Pingdi capsule on insulin resistance in metabolism syndrome was confirmed with good efficacy.
