中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
29期
97-99
,共3页
复方青黛丸%复方氨肽素%银屑病
複方青黛汍%複方氨肽素%銀屑病
복방청대환%복방안태소%은설병
Compound Qingdai pill%Compound antaisu%Psoriasis
目的：观察复方青黛丸联合复方氨肽素治疗进行期寻常型银屑病的疗效和安全性。方法：选取本科2011年10月-2013年11月收治的101例进行期寻常型银屑病患者，按照随机数字表法将其分为联合治疗组51例和对照组50例，联合治疗组采用内服复方青黛丸、复方氨肽素片，外用复方氟米松软膏治疗；对照组除不用复方青黛丸外，其余用药均与治疗组相同。连续8周为一疗程，治疗期间每周患者复诊1次，观察比较两组患者的临床疗效及不良反应情况。结果：治疗1个疗程后，联合治疗组的总有效率80.39%（41/51）明显高于对照组的60.00%（30/50），差异有统计学意义（χ2=5.028，P<0.05）。联合治疗组的平均起效时间（10.7±3.3）d明显短于对照组的（13.9±5.4）d，差异有统计学意义（t=3.601，P<0.05）。而两组的不良反应发生率无明显差异（P>0.05）。结论：两药联合治疗进行期寻常型银屑病的疗效显著，不良反应少，安全性高，值得临床推广。
目的：觀察複方青黛汍聯閤複方氨肽素治療進行期尋常型銀屑病的療效和安全性。方法：選取本科2011年10月-2013年11月收治的101例進行期尋常型銀屑病患者，按照隨機數字錶法將其分為聯閤治療組51例和對照組50例，聯閤治療組採用內服複方青黛汍、複方氨肽素片，外用複方氟米鬆軟膏治療；對照組除不用複方青黛汍外，其餘用藥均與治療組相同。連續8週為一療程，治療期間每週患者複診1次，觀察比較兩組患者的臨床療效及不良反應情況。結果：治療1箇療程後，聯閤治療組的總有效率80.39%（41/51）明顯高于對照組的60.00%（30/50），差異有統計學意義（χ2=5.028，P<0.05）。聯閤治療組的平均起效時間（10.7±3.3）d明顯短于對照組的（13.9±5.4）d，差異有統計學意義（t=3.601，P<0.05）。而兩組的不良反應髮生率無明顯差異（P>0.05）。結論：兩藥聯閤治療進行期尋常型銀屑病的療效顯著，不良反應少，安全性高，值得臨床推廣。
목적：관찰복방청대환연합복방안태소치료진행기심상형은설병적료효화안전성。방법：선취본과2011년10월-2013년11월수치적101례진행기심상형은설병환자，안조수궤수자표법장기분위연합치료조51례화대조조50례，연합치료조채용내복복방청대환、복방안태소편，외용복방불미송연고치료；대조조제불용복방청대환외，기여용약균여치료조상동。련속8주위일료정，치료기간매주환자복진1차，관찰비교량조환자적림상료효급불량반응정황。결과：치료1개료정후，연합치료조적총유효솔80.39%（41/51）명현고우대조조적60.00%（30/50），차이유통계학의의（χ2=5.028，P<0.05）。연합치료조적평균기효시간（10.7±3.3）d명현단우대조조적（13.9±5.4）d，차이유통계학의의（t=3.601，P<0.05）。이량조적불량반응발생솔무명현차이（P>0.05）。결론：량약연합치료진행기심상형은설병적료효현저，불량반응소，안전성고，치득림상추엄。
Objective:To observe the curative effect and safety of compound Qingdai pill combined with compound antaisu in treatment of active stage psoriasis vulgaris.Method:101 patients with active stage psoriasis vulgaris in our department from October 2011 to November 2013 were selected,they were divided into the combined treatment group for 51 cases and the control group for 50 cases according to the random number table method.The combined treatment group was given compound Qingdai pill combined with compound Amino-polypeptide tablets orally,compound Flumetasone Ointment for external use.The control group was given the same drug as the treatment group,except for compound Qingdai pill.For 8 weeks as 1 course of treatment,during treatment with 1 times a week to visit,the clinical effect and adverse reaction between the two groups were observed and compared.Result:After 1 course,the total effective rate of combined treatment group was 80.39%(41/51),it was significantly higher than 60.00%(30/50)of control group,the difference was statistically significant( χ2=5.028,P<0.05).The average onset time of combined treatment group was(10.7±3.3)d,it was significantly shorter than(13.9±5.4)d of control group,the difference was statistically significant(t=3.601,P<0.05).There was no significant difference in the incidence of adverse reaction between two groups(P>0.05).Conclusion:The two drugs in the treatment of psoriasis vulgaris has obvious curative effect,less adverse reaction,high security,is worthy of clinical promotion.
