中国医药导报
中國醫藥導報
중국의약도보
CHINA MEDICAL HERALD
2014年
29期
68-71
,共4页
白霉素%沙丁胺醇%布地奈德%雾化吸入%毛细支气管炎
白黴素%沙丁胺醇%佈地奈德%霧化吸入%毛細支氣管炎
백매소%사정알순%포지내덕%무화흡입%모세지기관염
Leucomycin%Salbutamol%Budesonide%Atomization inhalation%Bronchiolitis
目的：探讨白霉素联合沙丁胺醇布地奈德雾化吸入治疗毛细支气管炎的临床效果。方法选取承德市兴隆县妇幼保健院2011年10月~2013年10月诊治的毛细支气管炎患者228例，采用数字表随机法分为两组，114例患者采用沙丁胺醇布地奈德雾化吸入治疗为对照组，114例患者采用白霉素联合沙丁胺醇布地奈德雾化吸入治疗为观察组，比较两组患者的病症改善情况、临床疗效、不良反应情况。结果观察组患者喘息消失时间、气促消失时间、肺部湿啰音消失时间、退热时间、咳嗽消失时间、呼吸困难消失时间、肺部哮鸣音消失时间、住院时间均明显短于对照组，观察组患者总有效率(98.2%)明显高于对照组(88.6%)，差异均有统计学意义(P<0.05或P<0.01)。观察组患者不良反应发生率为9.6%，对照组为7.9%，差异无统计学意义(P>0.05)。结论白霉素联合沙丁胺醇布地奈德雾化吸入疗法是治疗毛细支气管炎的有效方法，可明显改善患者的临床病症，临床疗效显著且安全性高，值得临床推广使用。
目的：探討白黴素聯閤沙丁胺醇佈地奈德霧化吸入治療毛細支氣管炎的臨床效果。方法選取承德市興隆縣婦幼保健院2011年10月~2013年10月診治的毛細支氣管炎患者228例，採用數字錶隨機法分為兩組，114例患者採用沙丁胺醇佈地奈德霧化吸入治療為對照組，114例患者採用白黴素聯閤沙丁胺醇佈地奈德霧化吸入治療為觀察組，比較兩組患者的病癥改善情況、臨床療效、不良反應情況。結果觀察組患者喘息消失時間、氣促消失時間、肺部濕啰音消失時間、退熱時間、咳嗽消失時間、呼吸睏難消失時間、肺部哮鳴音消失時間、住院時間均明顯短于對照組，觀察組患者總有效率(98.2%)明顯高于對照組(88.6%)，差異均有統計學意義(P<0.05或P<0.01)。觀察組患者不良反應髮生率為9.6%，對照組為7.9%，差異無統計學意義(P>0.05)。結論白黴素聯閤沙丁胺醇佈地奈德霧化吸入療法是治療毛細支氣管炎的有效方法，可明顯改善患者的臨床病癥，臨床療效顯著且安全性高，值得臨床推廣使用。
목적：탐토백매소연합사정알순포지내덕무화흡입치료모세지기관염적림상효과。방법선취승덕시흥륭현부유보건원2011년10월~2013년10월진치적모세지기관염환자228례，채용수자표수궤법분위량조，114례환자채용사정알순포지내덕무화흡입치료위대조조，114례환자채용백매소연합사정알순포지내덕무화흡입치료위관찰조，비교량조환자적병증개선정황、림상료효、불량반응정황。결과관찰조환자천식소실시간、기촉소실시간、폐부습라음소실시간、퇴열시간、해수소실시간、호흡곤난소실시간、폐부효명음소실시간、주원시간균명현단우대조조，관찰조환자총유효솔(98.2%)명현고우대조조(88.6%)，차이균유통계학의의(P<0.05혹P<0.01)。관찰조환자불량반응발생솔위9.6%，대조조위7.9%，차이무통계학의의(P>0.05)。결론백매소연합사정알순포지내덕무화흡입요법시치료모세지기관염적유효방법，가명현개선환자적림상병증，림상료효현저차안전성고，치득림상추엄사용。
Objective To investigate clinical effect of Leucomycin combined with Salbutamol Budesonide atomization inhalation in the treatment of bronchiolitis. Methods Two hundred and twenty eight patients with bronchiolitis were se-lected in Maternal and Child Health Hospital of Xinglong County in Chengde City from October 2011 to October 2013, who were randomly divided into two groups. 114 patients treated with Salbutamol Budesonide atomization inhalation were as control group. 114 patients treated with Leucomycin combined with Salbutamol Budesonide atomization inhala-tion were as observation group. Symptoms improvement, clinical efficacy, adverse reactions were compared between two groups. Results Wheezing disappearance time, shortness breath disappearance time, pulmonary rales disappearance time, cooling time, cough disappearance time, breathing difficulties disappearance time, pulmonary wheezing disappear-ance time, hospitalization time in observation group were significantly shorter than control group, total effective rate (98.2%) in observation group was significantly higher than that of control group (88.6%), the differences were statisti-cally significant (P< 0.05 or P< 0.01). Incidence of adverse reactions in observation group was 9.6%, which of control group was 7.9%, the difference was not statistically significant (P > 0.05). Conclusion Leucomycin combined with Salbutamol Budesonide atomization inhalation is an effective method in treatment of bronchiolitis, which can significant-ly improve clinical symptoms, has significant clinical effect and high security, which is worthy of clinical use.
