CAJ | 학술논문

目的：调查慢性病患者用药情况和药学知识知晓情况，分析影响患者合理用药的因素，为慢性病患者药学服务模式建立提供数据支持。方法通过调查问卷对门诊和社区386例慢性病患者的用药情况和用药知识掌握情况进行调查，合理用药相关影响因素采用单因素和多因素Logistic回归分析。结果386例患者中，心、脑血管疾病构成比最高52．37％，呼吸系统疾病、肌肉骨骼系统疾病分别为13．80％、11．50％；386例患者平均得分（1．76±0．78）分，用药知识掌握情况属于较差水平；单因素分析结果显示，合理用药患者与未合理用药患者在疾病种数、病程、费用支付形式、婚姻状态、月收入、学历水平、参加药物知识讲座、联合用药方面比较差异有统计学意义（P＜0．05）；多因素Logistic回归分析结果显示，学历水平、参加药物知识讲座、联合用药、疾病种数对慢性病患者合理用药有显著影响（P＜0．05）。结论慢性病患者用药知识掌握情况欠佳，用药不合理行为较多。学历水平、参加药物知识讲座、联合用药、疾病种数对慢性病患者合理用药有较大影响。临床药师应根据慢性病患者的用药特点建立有效的药学服务模式。
목적：조사만성병환자용약정황화약학지식지효정황，분석영향환자합리용약적인소，위만성병환자약학복무모식건립제공수거지지。방법통과조사문권대문진화사구386례만성병환자적용약정황화용약지식장악정황진행조사，합리용약상관영향인소채용단인소화다인소Logistic회귀분석。결과386례환자중，심、뇌혈관질병구성비최고52．37％，호흡계통질병、기육골격계통질병분별위13．80％、11．50％；386례환자평균득분（1．76±0．78）분，용약지식장악정황속우교차수평；단인소분석결과현시，합리용약환자여미합리용약환자재질병충수、병정、비용지부형식、혼인상태、월수입、학력수평、삼가약물지식강좌、연합용약방면비교차이유통계학의의（P＜0．05）；다인소Logistic회귀분석결과현시，학력수평、삼가약물지식강좌、연합용약、질병충수대만성병환자합리용약유현저영향（P＜0．05）。결론만성병환자용약지식장악정황흠가，용약불합리행위교다。학력수평、삼가약물지식강좌、연합용약、질병충수대만성병환자합리용약유교대영향。림상약사응근거만성병환자적용약특점건립유효적약학복무모식。
Objective To investigate the medical and pharmaceutical knowledge of patients with chronic diseases and analyse the influence factors of rational administration in patients ,to provid data to support the establishment of pharmaceutical service mode . Methods 386 cases of patients with chronic diseases were asked to finish the questionnaires for the medical and pharmaceutical knowledge ,and factors affecting the rational drug were analyzed by single factor and multiple factors Logistic regression analysis . Results Among the 386 patients ,cardiovascular and celebralvascular disease ratio was the highest(53 .3% ) ,followed by respiratory system diseases(13 .8% ) and the musculoskeletal system diseases (11 .50% );The averaged score of 386 patients was 1 .76 ± 0 .78 , medication knowledge was at a general level;single factor analysis results showed that there was significant difference(P<0 .05) between rational drug-use and abuse of drugs among patients in number ,form of payment ,marital status ,income ,education level , taking drug knowledge lectures ,combined treatment .Multivariate Logistic regression analysis showed that education level ,partici-pation in lectures ,drug combination ,disease species had a significant impact on the rational drug use among patients with chronic disease(P<0 .05) .Conclusion The pharmaceutical knowledge that patients with chronic disease mastered is unsatisfactory ;and unreasonable behavior of medication is common scence .Education level ,participation in lectures ,drug combination ,the number of diseases have great influence on the rational use of drugs in patients with chronic diseases .A kind of effective pharmaceutical service mode should be established for patients with chronic diseases by clinical pharmacists .This is a very meaningful work for rational ad-ministration .