CAJ | 학술논문

目的：研究女性吸毒人群急性心肌梗死（AMI）患者的临床和冠状动脉病变特征。方法回顾性分析2006年2月至2012年6月，武警广东总队医院司法病区中心收治的70例经冠状动脉造影确诊的女性A M I患者。结果70例女性患者中66例为急性ST段抬高型心肌梗死（STEMI），4例为急性非ST段抬高型心急梗死（NSTEMI）；67例为阻塞性病变，进行了经皮再血管化治疗；随吸毒时间的延长及合并危险因素的增加，AMI的发生率升高（P＜0．05）。冠状动脉造影资料结果分析发现：不同吸毒时间的AMI患者多为单支病变，比例明显高于三支病变和主干病变，其中血管以左前降支病变最为常见，其次为右冠状动脉、回旋支。三支及主干病变在吸毒时间小于5年的患者中少见，随吸毒时间延长，三支及主干病变增加。随访期间有1例在监押场所猝死，5例因心绞痛发作再住院。结论女性吸毒人群AMI患者多为急性STEMI ，以单支、阻塞性病变多见，前降支为最常见的罪犯血管。吸毒时间越长，合并危险因素越多，AM I的发生率越高。
목적：연구녀성흡독인군급성심기경사（AMI）환자적림상화관상동맥병변특정。방법회고성분석2006년2월지2012년6월，무경엄동총대의원사법병구중심수치적70례경관상동맥조영학진적녀성A M I환자。결과70례녀성환자중66례위급성ST단태고형심기경사（STEMI），4례위급성비ST단태고형심급경사（NSTEMI）；67례위조새성병변，진행료경피재혈관화치료；수흡독시간적연장급합병위험인소적증가，AMI적발생솔승고（P＜0．05）。관상동맥조영자료결과분석발현：불동흡독시간적AMI환자다위단지병변，비례명현고우삼지병변화주간병변，기중혈관이좌전강지병변최위상견，기차위우관상동맥、회선지。삼지급주간병변재흡독시간소우5년적환자중소견，수흡독시간연장，삼지급주간병변증가。수방기간유1례재감압장소졸사，5례인심교통발작재주원。결론녀성흡독인군AMI환자다위급성STEMI ，이단지、조새성병변다견，전강지위최상견적죄범혈관。흡독시간월장，합병위험인소월다，AM I적발생솔월고。
Objective To study the clinical and coronary characteristics of drug abuse women patients with acute myocardial in-farction .Methods Data of 70 women patients ,who were diagnosed with acute myocardial infarction(AMI)and underwent emergent coronary angiography in department of jurisdiction ,Guangdong Provincial Corps Hospital ,Chinese People′s Armed Police Force from January 2006 to July 2012 ,were analyzed .Results 66 of 70 were ST-segment elevated myocardial infarction ,4 were non-ST-segment elevated myocardial infarction ;67 of 70 were obstructive lesion ,underwent percutaneous coronary intervention .With the drug abuse time prolonging ,the combining risk factors increased ,the occurrence rate of AMI increased(P<0 .05) .Data of coronary angiography showed that the culprit vessels of most AMI patients with different drug abuse time were single vessel lesion ,which was significantly higher than the rate of three vessel and main stem .the most common culprit vessel was the left anterior descending artery ,followed by the right coronary artery and left circumflex artery lesion .three vessel and main stem lesion were short in pa-tients of drug abuse time <5 years ,with the prolonging of drug abuse time ,three vessel and main stem lesion increased .There was 1 death example in prison and 5 re-admission fore agnia during the follow-up .Conclusion Most AMI in drug abuse women patients with acute myocardial infarction is STEMI .Single vessel and obstructive lesion is the most common .The most common culprit ves-sel was the left anterior descending artery .Most female patients were complicated with congenital coronary malformation or autoim-mune disease .With the prolonging of drug abuse time and increasing of combining risk factors ,the rate of AMI increases .