CAJ | 학술논문

目的：观察丹参酮ⅡA 对心血管疾病患者心血管功能及血流动力学指标的影响。方法将2011年6月至2012年5月心血管疾病确诊患者120例分为治疗组（60例）和对照组（60例），两组均给予相应的常规治疗，治疗组加用丹参酮ⅡA 治疗，观察两组患者治疗前后心率、血压、心功能指标和血流动力学指标等参数变化。结果治疗组患者心率、血压、心功能指标和血流动力学指标的改善情况优于对照组，两组间差异有统计学意义（P ＜0．05）。结论丹参酮ⅡA 能够有效保护心血管功能、增加心肌收缩力、降低血液黏稠度，效果显著，具有较好的临床应用价值。
목적：관찰단삼동ⅡA 대심혈관질병환자심혈관공능급혈류동역학지표적영향。방법장2011년6월지2012년5월심혈관질병학진환자120례분위치료조（60례）화대조조（60례），량조균급여상응적상규치료，치료조가용단삼동ⅡA 치료，관찰량조환자치료전후심솔、혈압、심공능지표화혈류동역학지표등삼수변화。결과치료조환자심솔、혈압、심공능지표화혈류동역학지표적개선정황우우대조조，량조간차이유통계학의의（P ＜0．05）。결론단삼동ⅡA 능구유효보호심혈관공능、증가심기수축력、강저혈액점주도，효과현저，구유교호적림상응용개치。
Objective To observe the pharmacological activities and clinical effect of Tanshinone ⅡA on cardi-ovascular.Methods During June 2011 to May 2012,120 cardiovascular patients were diveded into treatment group and control group.Patients in both group were given corresponding regular treatment.Meanwhile,patients in treat-ment group were added Tanshinone ⅡA treatment.Before and after treatment,patients in the two groups were ob-served the changes of heart rat,blood pressure,cardiac fuction and hemodynamics indexs.Results Compared with control group,indexs of patients in the treatment group improved even more significantly after treatment.The differ-ences between the two groups were statistically significant(P <0.05).Conclusion Tanshinone ⅡA cloud effective protect cardiovascular function,strength myocardial contractility and lower blood viscosity,which has a good value in clinical application.