CAJ | 학술논문

目的：了解兰州地区无偿献血者艾滋病病毒（HIV）感染情况，有针对性地采取措施，保障血液安全。方法采用2种不同厂家的酶联免疫吸附试验（ELISA）试剂，对献血者标本进行抗-HIV 筛查，初筛阳性标本用免疫印迹法（WB）进行确证试验。结果兰州地区2009年1月至2012年12月抗-HIV 确证阳性32例，平均感染率为0．15‰；男性高于女性；年龄以18～35岁为主；涉及多个行业；学生及高学历人群的感染率有升高趋势。抗-HIV初筛与确证试验的结果符合率较低；随着 S/CO 值的增高，与确证试验的阳性符合率也随之升高。结论兰州地区无偿献血者抗-HIV 阳性率有逐年增高及年轻化的趋势，应加强献血者献血前咨询、筛查及艾滋病防治知识宣传。通过调整检测试剂及方法，提高抗-HIV 初筛与确证试验的结果符合率。探讨献血者的召回及归队策略，在保证血液安全的前提下，减少因假阳性结果造成的献血员流失，稳定无偿献血者队伍。
목적：료해란주지구무상헌혈자애자병병독（HIV）감염정황，유침대성지채취조시，보장혈액안전。방법채용2충불동엄가적매련면역흡부시험（ELISA）시제，대헌혈자표본진행항-HIV 사사，초사양성표본용면역인적법（WB）진행학증시험。결과란주지구2009년1월지2012년12월항-HIV 학증양성32례，평균감염솔위0．15‰；남성고우녀성；년령이18～35세위주；섭급다개행업；학생급고학력인군적감염솔유승고추세。항-HIV초사여학증시험적결과부합솔교저；수착 S/CO 치적증고，여학증시험적양성부합솔야수지승고。결론란주지구무상헌혈자항-HIV 양성솔유축년증고급년경화적추세，응가강헌혈자헌혈전자순、사사급애자병방치지식선전。통과조정검측시제급방법，제고항-HIV 초사여학증시험적결과부합솔。탐토헌혈자적소회급귀대책략，재보증혈액안전적전제하，감소인가양성결과조성적헌혈원류실，은정무상헌혈자대오。
Objective To understand the HIV infection situation among unpaid blood donors in Lanzhou area, take effective measures to ensure blood safety.Methods Two different enzyme-linked immunosorbent assay(ELISA) reagent were employed to screen anti-HIV of unpaid blood donors specimens,western blotting(WB)confirmatory test was used for early screening positive specimens.Results From January 2009 to December 2012,32 cases were confirmed anti-HIV positive and the average infection rate was 0.15‰The infection rate of men was higher than that of women;18~35 years was the main groups,involved multiple industries;there was a rising trend in students and highly educated population.The coincidence rate of anti-HIV screening and confirmatory test was lower,but with the S/CO value increasing,the coincidence rate was also rising.Conclusion Anti-HIV positive rate has increased year by year and trended younger in Lanzhou area,so it is necessary to strengthen the consultation,screening and the propa-ganda of HIV/AIDS prevention and control knowledge before the blood supply.By adjusting the detection reagent and methods,improve the anti-HIV early screening and confirmatory test results coincidence rate.